SH2D3A
From Wikipedia, the free encyclopedia
| SH2 domain containing 3A | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||
| Symbols | SH2D3A; NSP1 | ||||||||||||
| External IDs | OMIM: 604721 HomoloGene: 48351 GeneCards: SH2D3A Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
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| More reference expression data | |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 10045 | n/a | |||||||||||
| Ensembl | ENSG00000125731 | n/a | |||||||||||
| UniProt | Q9BRG2 | n/a | |||||||||||
| RefSeq (mRNA) | NM_005490 | n/a | |||||||||||
| RefSeq (protein) | NP_005481 | n/a | |||||||||||
| Location (UCSC) | Chr 19: 6.75 – 6.77 Mb | n/a | |||||||||||
| PubMed search | n/a | ||||||||||||
SH2 domain-containing protein 3A is a protein that in humans is encoded by the SH2D3A gene.[1][2]
Interactions
SH2D3A has been shown to interact with Epidermal growth factor receptor.[1]
References
- ↑ 1.0 1.1 Lu Y, Brush J, Stewart TA (May 1999). "NSP1 defines a novel family of adaptor proteins linking integrin and tyrosine kinase receptors to the c-Jun N-terminal kinase/stress-activated protein kinase signaling pathway". J Biol Chem 274 (15): 10047–52. doi:10.1074/jbc.274.15.10047. PMID 10187783.
- ↑ "Entrez Gene: SH2D3A SH2 domain containing 3A".
Further reading
- Near RI, Zhang Y, Makkinje A et al. (2007). "AND-34/BCAR3 differs from other NSP homologs in induction of anti-estrogen resistance, cyclin D1 promoter activation and altered breast cancer cell morphology". J. Cell. Physiol. 212 (3): 655–65. doi:10.1002/jcp.21059. PMC 2640322. PMID 17427198.
- Vervoort VS, Roselli S, Oshima RG, Pasquale EB (2007). "Splice variants and expression patterns of SHEP1, BCAR3 and NSP1, a gene family involved in integrin and receptor tyrosine kinase signaling". Gene 391 (1–2): 161–70. doi:10.1016/j.gene.2006.12.016. PMC 1876674. PMID 17270363.
- Benzinger A, Muster N, Koch HB et al. (2005). "Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer". Mol. Cell Proteomics 4 (6): 785–95. doi:10.1074/mcp.M500021-MCP200. PMID 15778465.
- Gerhard DS, Wagner L, Feingold EA et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Ota T, Suzuki Y, Nishikawa T et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Clark HF, Gurney AL, Abaya E et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
- Strausberg RL, Feingold EA, Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
External links
- SH2D3A human gene location in the UCSC Genome Browser.
- SH2D3A human gene details in the UCSC Genome Browser.
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