Søren Brunak

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Søren Brunak

Søren Brunak speaking the at the Intelligent Systems for Molecular Biology conference in 2010
Born 1958 (age 5556)[1]
Residence Copenhagen, Denmark
Nationality Danish
Fields Bioinformatics
Institutions Technical University of Denmark
Alma mater University of Copenhagen
Technical University of Denmark
Known for Development of computational tools for protein sequence analysis
Notable awards Dir. Ib Henriksens Price for Outstanding Science Achievement, Villum Kann Rasmussen Price for Research within the Natural and Technical Sciences.
Website
www.cbs.dtu.dk

Søren Brunak, Ph.D. (born 1958) is a Danish physical and biological scientist working in bioinformatics. He is the director of the Center for Biological Sequence Analysis at the Department of Systems Biology of the Technical University of Denmark[2][3] since 1993.[4]

Education

Søren Brunak obtained his Master of Science degree in Physics, in 1987 at the Niels Bohr Institute, University of Copenhagen, in 1991 his Ph.D. in Computational Biology at the Department of Structural Properties of Materials, Technical University of Denmark, and in 2002 a Dr.phil. (honoris causa) from the Natural Science Faculty of the Stockholm University.

Career

He is member of the Danish Academy for the Natural Sciences since 1997, member of the Board of directors of the International Society for Computational Biology since 2001, of the Danish Academy of Technical Sciences since 2002, and of the Danish Royal Society of Science and Letters since 2004.

He is part of the scientific advisory committees of several scientific organizations, such as EMBL (Heidelberg), Ensembl at the European Bioinformatics Institute/Sanger Centre (chairman), the Bioinformatics Advisory Committee at the European Bioinformatics Institute (chairman), and the Max Planck Institute for Molecular Genetics (Berlin).

Dir. Ib Henriksens Price for Outstanding Science Achievement. Villum Kann Rasmussen Price for Research within the Natural and Technical Sciences (2006).

Research

Brunak's main research is in Bioinformatics and systems biology. In particular, the prediction of protein properties from their sequences. For example, protein cleavage sites, protein glycosilation sites, phosphorylation sites, transmembrane helices, etc.[5][6][7][8]

Positions and awards

  • 1993–present: Member: Danish Academy for the Natural Sciences (DNA).
  • 1997-2003: Board of directors BioCentrum-DTU.
  • 1998: Bjerrum-Brøndsted-Lang Award from the Royal Danish Academy of Sciences and Letters.
  • 2000–present: Board of directors, Selskabet for Naturlærens Udbredelse.
  • 2000–present: Nordic Bioinformatics Network Program Board.
  • 2001-2004: Board of directors, International Society for Computational Biology.
  • 2001–present: Member of the Danish Academy of Technical Sciences.
  • 2002: Dir. Ib Henriksens Price for Outstanding Science Achievement.
  • 2004–present: Member: Danish Royal Society of Science and Letters.
  • 2006: Villum Kann Rasmussen Price for Research within the Natural and Technical Sciences.

Publications

  • Brunak S, Lautrup B (1990). Neural Networks - Computers with Intuition. World Scientific Publishing. ISBN 9971-5-0939-3. 
  • Bohr H, Brunak S, ed. (1994). Protein Structure by Distance Analysis. Amsterdam: IOS Press. ISBN 90-5199-161-4. 
  • Bohr H, Brunak S, ed. (1995). Protein Folds: A Distance Based Approach. Boca Raton: CRC Press. 
  • Baldi P, Brunak S (1998). Bioinformatics: The Machine Learning Approach. MIT Press. ISBN 0-262-02442-X. 
  • Baldi P, Brunak S (2001). Bioinformatics: The Machine Learning Approach (2nd ed.). MIT Press. 
  • Ussery DW, Brunak S (2001). "Genome Sequence Databases". In S. Brenner and J.H. Miller. Encyclopedia of Genetics. Academic Press. 
  • Baldi P, Brunak S, Frasconi P, Pollastri G, Soda G (2001). "Bidirectional Dynamics for Protein Secondary Structure Prediction". In R. Sun and C. Lee Giles. Sequence Learning - Paradigms, Algorithms, and Applications. Springer Verlag. pp. 80–104. 
  • Lund O, Nielsen M, Lundegaard C, Kesmir C, Brunak S (2005). Immunological Bioinformatics. MIT Press. 

References

  1. http://viaf.org/viaf/200207241/
  2. Soren Brunak page at the Technical University of Denmark
  3. Soren Brunak Biography
  4. Søren Brunak from the Scopus bibliographic database
  5. Nielsen, H.; Engelbrecht, J.; Brunak, S.; Von Heijne, G. (1997). "Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites". Protein Engineering Design and Selection 10: 1–6. doi:10.1093/protein/10.1.1. PMID 9051728. 
  6. Dyrløv Bendtsen, J.; Nielsen, H.; Von Heijne, G.; Brunak, S. (2004). "Improved Prediction of Signal Peptides: SignalP 3.0". Journal of Molecular Biology 340 (4): 783–795. doi:10.1016/j.jmb.2004.05.028. PMID 15223320. 
  7. Brunak, S.; Engelbrecht, J.; Knudsen, S. (1990). "Neural network detects errors in the assignment of mRNA splice sites". Nucleic Acids Research 18 (16): 4797–4801. doi:10.1093/nar/18.16.4797. PMC 331948. PMID 2395643. 
  8. Brunak, S.; Engelbrecht, J.; Knudsen, S. (1990). "Cleaning up gene databases". Nature 343 (6254): 123–123. doi:10.1038/343123a0. PMID 2296305. 


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