Ro5-2904

From Wikipedia, the free encyclopedia
Ro5-2904
Systematic (IUPAC) name
5-phenyl-7-(trifluoromethyl)-1,3-dihydro-1,4-benzodiazepin-2-one
Clinical data
Legal status ?
Identifiers
CAS number 2285-16-7 YesY
ATC code None
PubChem CID 16795
Chemical data
Formula C16H11F3N2O 
Mol. mass 304.267
 YesY (what is this?)  (verify)

Ro5-2904[1] (Triflunordazepam) is a drug which is a benzodiazepine derivative with high GABAA receptor affinity, and has anticonvulsant effects.[2][3]

See also

References

  1. ↑ DE Patent 1136709
  2. ↑ Archives Internationales de Pharmacodynamie et de Therapie. (1965). Vol 154, p 131.
  3. ↑ So SS, Karplus M (December 1996). "Genetic neural networks for quantitative structure-activity relationships: improvements and application of benzodiazepine affinity for benzodiazepine/GABAA receptors". Journal of Medicinal Chemistry 39 (26): 5246–56. doi:10.1021/jm960536o. PMID 8978853. 
Benzodiazepine derivatives
1,4-Benzodiazepines
1,5-Benzodiazepines
2,3-Benzodiazepines *
Triazolobenzodiazepines
Imidazobenzodiazepines
Oxazolobenzodiazepines
Thienodiazepines
Pyridodiazepines
Pyrazolodiazepines
Pyrrolodiazepines
Tetrahydroisoquinobenzodiazepines
Benzodiazepine prodrugs
* atypical activity profile (not GABAA receptor ligands)


This article is issued from Wikipedia. The text is available under the Creative Commons Attribution/Share Alike; additional terms may apply for the media files.