Rimexolone

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Rimexolone
Systematic (IUPAC) name
(8S,9S,10R,11S,13S,14S,16R,17S)-11-Hydroxy-10,13,16,17-tetramethyl-17-propanoyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
Clinical data
AHFS/Drugs.com monograph
MedlinePlus a606003
Pregnancy cat. C (US)
Legal status ?
Routes occular
Identifiers
CAS number 49697-38-3 YesY
ATC code H02AB12 S01BA13
PubChem CID 16051942
DrugBank DB00896
ChemSpider 10482044 YesY
UNII O7M2E4264D YesY
KEGG D05729 YesY
ChEMBL CHEMBL1200617 N
Chemical data
Formula C24H34O3 
Mol. mass 370.525 g/mol
 N (what is this?)  (verify)

Rimexolone is a glucocorticoid steroid used to treat inflammation in the eye.[1] It is marketed as a 1% eye drop suspension under the trade name Vexol by Alcon Laboratories.

References

  1. ↑ Kavuncu S, Horoz H, Ardagil A, Erbil HH (August 2008). "Rimexolone 1% versus prednisolone acetate in preventing early postoperative inflammation after cataract surgery". Int Ophthalmol 28 (4): 281–5. doi:10.1007/s10792-007-9131-0. PMID 17762913. 


Corticosteroids – glucocorticoids and mineralocorticoids (H02)
(also A07EA, C05AA, D07, D10AA, R01AD, R03BA, S01BA, S02B, and S03B)
Mineralocorticoids
(3-one, 4-ene,
no FG at 16)
Glucocorticoids
(3-one, 4-ene,
11-FG,
17-hydroxy)
Pregnenedione
(+20-one)
Pregnadiene (+1-ene)
Pregnadienediol
(+21-hydroxy)
Pregnadienetriol
(+11-hydroxy)
Pregnatriene
(+2-ene)
Other/ungrouped
Aldosterone antagonists
Synthesis modifiers

M: END

anat/phys/devp/horm

noco (d)/cong/tumr, sysi/epon

proc, drug (A10/H1/H2/H3/H5)


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