Reinke's edema

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Reinke's edema
Classification and external resources

Reinke's edema
ICD-10 J38.4
ICD-9 478.6
DiseasesDB 32572

Reinke's edema, also known as polypoid degeneration, is the swelling of the vocal folds due to fluid collection (edema) in superficial lamina propria of vocal folds (Reinke's space). It is named after Friedrich B. Reinke.[1][2]

Presentation

Reinke's edema causes the vocal folds to swell giving them an uneven, sac-like appearance. They appear pale and translucent. Individuals with Reinke's Edema typically have low-pitched, husky voices, as they use false vocal folds for voice production.

Causes

Common causes of Reinke's edema include smoking, gastroesophageal reflux, hormonal changes such as hypothyroidism and chronic voice abuse.

Histology

Histopathology: biopsy of the vocal fold may be used to help in diagnosis in some cases. Histology shows oedema of the Reinke's space.

Treatment

The first course of treatment is to remove the source of the irritant (e.g. smoking cessation, vocal rest, etc.). This can be effective if done soon after development of the edema. Surgery is also an option and can result in some restoration of the voice but is ineffective in complete restoration of the voice to its original state. Decortication of the vocal folds, i.e. removal of a strip of epithelium, is done first on one side and 3–4 weeks later on the other side. Speech therapy is given for proper voice production.

See also

References

  1. synd/2653 at Who Named It?
  2. F. B. Reinke. Untersuchungen über das menschliche Stimmband. Fortschritte der Medizin, München, 1895, 13: 469-478.
Notes

External links

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