RNF39
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| Ring finger protein 39 | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | RNF39; HZF; HZFW; LIRF | ||||||||||||
| External IDs | OMIM: 607524 HomoloGene: 11891 GeneCards: RNF39 Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
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| More reference expression data | |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 80352 | 386454 | |||||||||||
| Ensembl | ENSG00000204618 | ENSMUSG00000036492 | |||||||||||
| UniProt | Q9H2S5 | A2RT81 | |||||||||||
| RefSeq (mRNA) | NM_025236 | NM_001099632 | |||||||||||
| RefSeq (protein) | NP_079512 | NP_001093102 | |||||||||||
| Location (UCSC) | Chr 6: 30.04 – 30.04 Mb | Chr 17: 36.94 – 36.95 Mb | |||||||||||
| PubMed search | |||||||||||||
RING finger protein 39 is a protein that in humans is encoded by the RNF39 gene.[1][2][3]
This gene lies within the major histocompatibility complex class I region on chromosome 6. Studies of a similar rat protein suggest that this gene encodes a protein that plays a role in an early phase of synaptic plasticity. Alternative splicing results in three transcript variants encoding different isoforms.[3]
References
- ↑ Coriton O, Lepourcelet M, Hampe A, Galibert F, Mosser J (Dec 2000). "Transcriptional analysis of the 69-kb sequence centromeric to HLA-J: a dense and complex structure of five genes". Mamm Genome 11 (12): 1127–31. doi:10.1007/s003350010213. PMID 11130983.
- ↑ Matsuo R, Asada A, Fujitani K, Inokuchi K (Nov 2001). "LIRF, a gene induced during hippocampal long-term potentiation as an immediate-early gene, encodes a novel RING finger protein". Biochem Biophys Res Commun 289 (2): 479–84. doi:10.1006/bbrc.2001.5975. PMID 11716498.
- ↑ 3.0 3.1 "Entrez Gene: RNF39 ring finger protein 39".
Further reading
- Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6.". Nature 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
- Orimo A, Yamagishi T, Tominaga N, et al. (2000). "Molecular cloning of testis-abundant finger Protein/Ring finger protein 23 (RNF23), a novel RING-B box-coiled coil-B30.2 protein on the class I region of the human MHC". Biochem. Biophys. Res. Commun. 276 (1): 45–51. doi:10.1006/bbrc.2000.3380. PMID 11006080.
- Hidaka M, Caruana G, Stanford WL, et al. (2000). "Gene trapping of two novel genes, Hzf and Hhl, expressed in hematopoietic cells". Mech. Dev. 90 (1): 3–15. doi:10.1016/S0925-4773(99)00234-8. PMID 10585558.
- Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
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