RNF13

From Wikipedia, the free encyclopedia

Ring finger protein 13

Identifiers

RNF13; RZF

External IDs

OMIM: 609247 HomoloGene: 13493 GeneCards: RNF13 Gene

Gene Ontology
Molecular function	• ubiquitin-protein ligase activity • zinc ion binding
Cellular component	• Golgi membrane • nuclear inner membrane • lysosomal membrane • endoplasmic reticulum membrane • integral to membrane • late endosome membrane
Biological process	• protein autoubiquitination
Sources: Amigo / QuickGO

Orthologs

Species

Human

Mouse

ENSG00000082996

ENSMUSG00000036503

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

Chr 3:
149.53 – 149.68 Mb

Chr 3:
57.74 – 57.84 Mb

PubMed search

RING finger protein 13 is a protein that in humans is encoded by the RNF13 gene.^[1]

The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. The specific function of this gene has not yet been determined. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.^[1]

References

↑ 1.0 1.1 "Entrez Gene: RNF13 ring finger protein 13".

Further reading

Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
Wesselkamper SC, McDowell SA, Medvedovic M, et al. (2006). "The role of metallothionein in the pathogenesis of acute lung injury.". Am. J. Respir. Cell Mol. Biol. 34 (1): 73–82. doi:10.1165/rcmb.2005-0248OC. PMC 2644192. PMID 16166738.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing.". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction.". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
Tranque P, Crossin KL, Cirelli C, et al. (1996). "Identification and characterization of a RING zinc finger gene (C-RZF) expressed in chicken embryo cells.". Proc. Natl. Acad. Sci. U.S.A. 93 (7): 3105–9. doi:10.1073/pnas.93.7.3105. PMC 39769. PMID 8610176.

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