RHBDF2
From Wikipedia, the free encyclopedia
| Rhomboid 5 homolog 2 (Drosophila) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||
| Symbols | RHBDF2; RHBDL5; RHBDL6; TOC | ||||||||||||
| External IDs | OMIM: 614404 MGI: 2442473 HomoloGene: 11612 GeneCards: RHBDF2 Gene | ||||||||||||
| |||||||||||||
| RNA expression pattern | |||||||||||||
 | |||||||||||||
| More reference expression data | |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 79651 | 217344 | |||||||||||
| Ensembl | ENSG00000129667 | ENSMUSG00000020806 | |||||||||||
| UniProt | Q6PJF5 | Q80WQ6 | |||||||||||
| RefSeq (mRNA) | NM_001005498 | NM_001167680 | |||||||||||
| RefSeq (protein) | NP_001005498 | NP_001161152 | |||||||||||
| Location (UCSC) | Chr 17: 74.47 – 74.5 Mb | Chr 11: 116.6 – 116.63 Mb | |||||||||||
| PubMed search | |||||||||||||
Rhomboid family member 2 is a protein that in humans is encoded by the RHBDF2 gene.[1][2] The alternative name iRhom2 has been proposed, in order to clarify that it is a catalytically inactive member of the rhomboid family of intramembrane serine proteases.[3][4]
References
- ↑ Puente XS, Sanchez LM, Overall CM, Lopez-Otin C (Jul 2003). "Human and mouse proteases: a comparative genomic approach". Nat Rev Genet 4 (7): 544–58. doi:10.1038/nrg1111. PMID 12838346.
- ↑ "Entrez Gene: RHBDF2 rhomboid 5 homolog 2 (Drosophila)".
- ↑ M. K. Lemberg, M. Freeman, Genome Res. 17, 1634 (2007)
- ↑ M. Zettl, C. Adrain, K. Strisovsky, V. Lastun, M. Freeman, Cell 145, 79 (2011)
Further reading
- Suzuki Y, Yamashita R, Shirota M et al. (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions". Genome Res. 14 (9): 1711–8. doi:10.1101/gr.2435604. PMC 515316. PMID 15342556.
- Puente XS, López-Otín C (2004). "A genomic analysis of rat proteases and protease inhibitors". Genome Res. 14 (4): 609–22. doi:10.1101/gr.1946304. PMC 383305. PMID 15060002.
- Ota T, Suzuki Y, Nishikawa T et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Strausberg RL, Feingold EA, Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Dias Neto E, Correa RG, Verjovski-Almeida S et al. (2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags". Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491–6. doi:10.1073/pnas.97.7.3491. PMC 16267. PMID 10737800.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
This article is issued from Wikipedia. The text is available under the Creative Commons Attribution/Share Alike; additional terms may apply for the media files.