Propiconazole

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Propiconazole^[1]

IUPAC name 1-[ [2-(2,4-dichlorophenyl)-4-propyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole
Identifiers
CAS number	60207-90-1^Y
PubChem	43234
ChemSpider	39402^Y
UNII	142KW8TBSR^Y
KEGG	C11121^Y
ChEBI	CHEBI:8489^Y
ChEMBL	CHEMBL560579^Y
Jmol-3D images	Image 1
SMILES Clc1ccc(c(Cl)c1)C2(OCC(O2)CCC)Cn3ncnc3
InChI InChI=1S/C15H17Cl2N3O2/c1-2-3-12-7-21-15(22-12,8-20-10-18-9-19-20)13-5-4-11(16)6-14(13)17/h4-6,9-10,12H,2-3,7-8H2,1H3^Y Key: STJLVHWMYQXCPB-UHFFFAOYSA-N^Y InChI=1/C15H17Cl2N3O2/c1-2-3-12-7-21-15(22-12,8-20-10-18-9-19-20)13-5-4-11(16)6-14(13)17/h4-6,9-10,12H,2-3,7-8H2,1H3 Key: STJLVHWMYQXCPB-UHFFFAOYAJ
Properties
Molecular formula	C₁₅H₁₇Cl₂N₃O₂
Molar mass	342.22038
Boiling point	180 °C at 0.1 mmHg
Solubility in water	100 ppm at 20 °C
Y (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Propiconazole is a triazole fungicide, also known as a DMI, or demethylation inhibiting fungicide due to its binding with and inhibiting the 14-alpha demethylase enzyme from demethylating a precursor to ergosterol. Without this demethylation step, the ergosterols are not incorporated into the growing fungal cell membranes, and cellular growth is stopped. Propiconazole is used agriculturally on turfgrasses grown for seed and aesthetic or athletic value, mushrooms, corn, wild rice, peanuts, almonds, sorghum, oats, pecans, apricots, peaches, nectarines, plums and prunes.^[2] It is also used in combination with permethrin in formulations of wood preserver.^[3] Propiconazole is a mixture^[4] of four stereoisomers and was first developed in 1979 by Janssen Pharmaceutica.^[5]

References

↑ Merck Index, 11th Edition, 7830.
↑ EXTOXNET
↑ See entry for Complete Wood Preservative
↑ L. Toribio, M. J. del Nozal, J. L. Bernal, J. J. Jeménez und C. Alonso, J. Chromatography A 2004, 1046, 249-253.
↑ W. T. Thomson. 1997. Agricultural Chemicals. Book IV: Fungicides. 12th edition. Thomson Publications, Fresno, CA

External links

Non-CCA Wood Preservatives: Guide to Selected Resources - National Pesticide Information Center

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