Pinosylvin synthase
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| pinosylvin synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.3.1.146 | ||||||||
| CAS number | 72994-49-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / EGO | ||||||||
| |||||||||
In enzymology, a pinosylvin synthase (EC 2.3.1.146) is an enzyme that catalyzes the chemical reaction
- 3 malonyl-CoA + cinnamoyl-CoA
4 CoA + pinosylvin + 4 CO2
Thus, the two substrates of this enzyme are malonyl-CoA and cinnamoyl-CoA, whereas its 3 products are CoA, pinosylvin, and CO2.
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is malonyl-CoA:cinnamoyl-CoA malonyltransferase (cyclizing). Other names in common use include stilbene synthase, and pine stilbene synthase. This enzyme participates in phenylpropanoid biosynthesis.
References
- Gehlert R, Schoppner A and Kindl H (1990). "Stilbene synthase from seedlings of Pinus sylvestris - purification and induction in response to fungal infection". Mol. Plant-Microbe Interaction 3: 444–449.
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