Pinosylvin synthase

From Wikipedia, the free encyclopedia
pinosylvin synthase
Identifiers
EC number 2.3.1.146
CAS number 72994-49-1
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a pinosylvin synthase (EC 2.3.1.146) is an enzyme that catalyzes the chemical reaction

3 malonyl-CoA + cinnamoyl-CoA \rightleftharpoons 4 CoA + pinosylvin + 4 CO2

Thus, the two substrates of this enzyme are malonyl-CoA and cinnamoyl-CoA, whereas its 3 products are CoA, pinosylvin, and CO2.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is malonyl-CoA:cinnamoyl-CoA malonyltransferase (cyclizing). Other names in common use include stilbene synthase, and pine stilbene synthase. This enzyme participates in phenylpropanoid biosynthesis.

References

    • Gehlert R, Schoppner A and Kindl H (1990). "Stilbene synthase from seedlings of Pinus sylvestris - purification and induction in response to fungal infection". Mol. Plant-Microbe Interaction 3: 444449. 
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