Phenindione

From Wikipedia, the free encyclopedia

Phenindione

Systematic (IUPAC) name
2-phenyl-1H-indene-1,3(2H)-dione
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy cat.	D (AU) Passes into breast milk
Legal status	?
Routes	Oral
Pharmacokinetic data
Protein binding	88%
Half-life	5 to 10 hours
Identifiers
CAS number	83-12-5^Y
ATC code	B01AA02
PubChem	CID 4760
DrugBank	DB00498
ChemSpider	4596^Y
UNII	5M7Y6274ZE^Y
KEGG	D08354^Y
ChEBI	CHEBI:8066^Y
ChEMBL	CHEMBL711^Y
Chemical data
Formula	C₁₅H₁₀O₂
Mol. mass	222.239 g/mol
SMILES O=C2c1ccccc1C(=O)C2c3ccccc3
InChI InChI=1S/C15H10O2/c16-14-11-8-4-5-9-12(11)15(17)13(14)10-6-2-1-3-7-10/h1-9,13H^Y Key:NFBAXHOPROOJAW-UHFFFAOYSA-N^Y
Y (what is this?) (verify)

Phenindione is an anticoagulant which functions as a Vitamin K antagonist.

Hypersensitivity has been observed.^[1]

References

Glycoprotein IIb/IIIa inhibitors	Abciximab Eptifibatide Tirofiban

ADP receptor/P2Y₁₂ inhibitors	thienopyridines Clopidogrel Prasugrel Ticlopidine nucleotide/nucleoside analogs Cangrelor Elinogrel Ticagrelor

Prostaglandin analogue (PGI2)	Beraprost Iloprost Prostacyclin Treprostinil

COX inhibitors	Acetylsalicylic acid/Aspirin^# Aloxiprin Carbasalate calcium Indobufen Triflusal

Thromboxane inhibitors	thromboxane synthase inhibitors Dipyridamole (+Aspirin) Picotamide receptor antagonist Terutroban^†

Phosphodiesterase inhibitors	Cilostazol Dipyridamole Triflusal

Other	Cloricromen Ditazole

Factor Xa inhibitors
(with some II inhibition)

Heparin group/ glycosaminoglycans/ (bind antithrombin)	low molecular weight heparin Bemiparin Certoparin Dalteparin Enoxaparin Nadroparin Parnaparin Reviparin Tinzaparin oligosaccharides Fondaparinux Idraparinux heparinoid Danaparoid Dermatan sulfate Sulodexide

Direct Xa inhibitors	xabans Apixaban Betrixaban Darexaban Edoxaban Otamixaban Rivaroxaban

Other

Non-medicinal

cell/phys (coag, heme, immu, gran), csfs

rbmg/mogr/tumr/hist, sysi/epon, btst

drug (B1/2/3+5+6), btst, trns

This article is issued from Wikipedia. The text is available under the Creative Commons Attribution/Share Alike; additional terms may apply for the media files.