Pegsunercept
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| Clinical data | |
|---|---|
| Legal status | investigational |
| Routes | subcutaneous injection |
| Pharmacokinetic data | |
| Bioavailability | N/A |
| Identifiers | |
| CAS number | 330988-75-5  |
| ATC code | None |
| UNII | Q5I7SFZ853  |
| KEGG | D05393 |
| Chemical data | |
| Formula | C502H758N154O165S16 |
| Mol. mass | 12,103 g/mol (protein part) |
| (what is this?) (verify) | |
Pegsunercept is a drug for the treatment of rheumatoid arthritis. As of January 2010, Phase II clinical trials have been completed.[1][2][3] It is being developed by Amgen.
Similarly to etanercept, pegsunercept is a soluble tumor necrosis factor receptor. Pegsunercept is a PEGylated protein.[3]
References
- ↑ ClinicalTrials.gov NCT00037700 Evaluation of the Efficacy of Combination Treatment With Anakinra and Pegsunercept in Improving Rheumatoid Arthritis
- ↑ ClinicalTrials.gov NCT00111423 Evaluating the Safety of Extended Treatment With Pegsunercept (PEG sTNF-RI)in Subjects With Rheumatoid Arthritis (RA)
- ↑ 3.0 3.1 Furst, D.; Fleischmann, R.; Kopp, E.; Schiff, M.; Edwards C, 3.; Solinger, A.; Macri, M.; 990136 Study, G. (2005). "A phase 2 dose-finding study of PEGylated recombinant methionyl human soluble tumor necrosis factor type I in patients with rheumatoid arthritis". The Journal of rheumatology 32 (12): 2303–2310. PMID 16331754.
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