Pazufloxacin

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Pazufloxacin

Systematic (IUPAC) name
(3R)-10-(1-aminocyclopropyl)-9-fluoro-3-methyl-7-oxo-1H,7H- [1,3]oxazino[5,4,3-ij]quinoline-carboxylic acid
Clinical data
AHFS/Drugs.com	International Drug Names
Legal status	?
Identifiers
CAS number	127046-18-8^Y
ATC code	J01MA18
PubChem	CID 65957
UNII	4CZ1R38NDI^Y
Chemical data
Formula	C₁₆H₁₅F N₂O₄
Mol. mass	318.29 g/mol
Y (what is this?) (verify)

Pazufloxacin (INN) is a fluoroquinolone antibiotic.^[1] It is sold in Japan under the brand names Pasil and Pazucross.

References

↑ Rubinstein, E. (2001). "History of quinolones and their side effects.". Chemotherapy. 47 Suppl 3: 3–8; discussion 44–8. doi:10.1159/000057838. PMID 11549783.

Antibacterials: nucleic acid inhibitors (J01E, J01M)

Antifolates
(inhibits
purine metabolism,
thereby inhibiting
DNA and RNA synthesis)

Sulfonamides
(DHPS inhibitor)

Short- acting	Sulfaisodimidine Sulfamethizole Sulfadimidine Sulfapyridine Sulfafurazole Sulfanilamide Prontosil Sulfathiazole Sulfathiourea

Intermediate- acting	Sulfamethoxazole Sulfadiazine^# Sulfamoxole

Long- acting	Sulfadimethoxine Sulfadoxine Sulfalene Sulfametomidine Sulfametoxydiazine Sulfamethoxypyridazine Sulfaperin Sulfamerazine Sulfaphenazole Sulfamazone

Other/ungrouped	Sulfacetamide Sulfadicramide Sulfametrole

Combinations

1st g.

Fluoro-
quinolones

2nd g.	Ciprofloxacin^# Enoxacin^‡ Fleroxacin^‡ Lomefloxacin Nadifloxacin Ofloxacin Norfloxacin Pefloxacin Rufloxacin

3rd g.	Balofloxacin Grepafloxacin^‡ Levofloxacin Pazufloxacin Sparfloxacin^‡ Temafloxacin^‡ Tosufloxacin

4th g.	Besifloxacin Clinafloxacin^† Garenoxacin Gemifloxacin Moxifloxacin Gatifloxacin^‡ Sitafloxacin Trovafloxacin^‡/Alatrofloxacin^‡ Prulifloxacin

Vet.	Danofloxacin Difloxacin Enrofloxacin Ibafloxacin Marbofloxacin Orbifloxacin Pradofloxacin Sarafloxacin

Related (DG)	Aminocoumarins: Novobiocin

Anaerobic DNA
inhibitors

Nitro- imidazole derivatives	Metronidazole^# Tinidazole Ornidazole

Nitrofuran derivatives	Nitrofurantoin^# Furazolidone^‡ Nifurtoinol

RNA synthesis

Rifamycins/ RNA polymerase	Rifampicin^# Rifabutin Rifapentine Rifaximin

bact (clas)

gr+f/gr+a (t)/gr-p (c)/gr-o

drug (J1p, w, n, m, vacc)

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