PGK1
From Wikipedia, the free encyclopedia
| Phosphoglycerate kinase 1 | |||||||||||||
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 PDB rendering based on 1hdi. | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | PGK1; MIG10; PGKA | ||||||||||||
| External IDs | OMIM: 311800 MGI: 97555 HomoloGene: 21542 ChEMBL: 2886 GeneCards: PGK1 Gene | ||||||||||||
| EC number | 2.7.2.3 | ||||||||||||
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| RNA expression pattern | |||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 5230 | 18655 | |||||||||||
| Ensembl | ENSG00000102144 | ENSMUSG00000062070 | |||||||||||
| UniProt | P00558 | P09411 | |||||||||||
| RefSeq (mRNA) | NM_000291 | NM_008828 | |||||||||||
| RefSeq (protein) | NP_000282 | NP_032854 | |||||||||||
| Location (UCSC) | Chr HG1426_PATCH: 77.33 – 77.39 Mb | Chr 12: 10.9 – 10.9 Mb | |||||||||||
| PubMed search | |||||||||||||
Phosphoglycerate kinase 1 is an enzyme that in humans is encoded by the PGK1 gene.[1][2][3]
Interactive pathway map
Click on genes, proteins and metabolites below to link to respective articles. [§ 1]
Glycolysis and Gluconeogenesis edit
- ↑ The interactive pathway map can be edited at WikiPathways: "GlycolysisGluconeogenesis_WP534".
References
- ↑ Michelson AM, Markham AF, Orkin SH (May 1983). "Isolation and DNA sequence of a full-length cDNA clone for human X chromosome-encoded phosphoglycerate kinase". Proc Natl Acad Sci U S A 80 (2): 472–6. doi:10.1073/pnas.80.2.472. PMC 393400. PMID 6188151.
- ↑ Singer-Sam J, Keith DH, Tani K, Simmer RL, Shively L, Lindsay S, Yoshida A, Riggs AD (May 1985). "Sequence of the promoter region of the gene for human X-linked 3-phosphoglycerate kinase]". Gene 32 (3): 409–17. doi:10.1016/0378-1119(84)90016-7. PMID 6099325.
- ↑ "Entrez Gene: PGK1 phosphoglycerate kinase 1".
Further reading
- Vishwanatha JK, Jindal HK, Davis RG (1992). "The role of primer recognition proteins in DNA replication: association with nuclear matrix in HeLa cells.". J. Cell. Sci. 101. ( Pt 1): 25–34. PMID 1533225.
- Fujii H, Kanno H, Hirono A, et al. (1992). "A single amino acid substitution (157 Gly----Val) in a phosphoglycerate kinase variant (PGK Shizuoka) associated with chronic hemolysis and myoglobinuria.". Blood 79 (6): 1582–5. PMID 1547346.
- Maeda M, Bawle EV, Kulkarni R, et al. (1992). "Molecular abnormalities of a phosphoglycerate kinase variant generated by spontaneous mutation.". Blood 79 (10): 2759–62. PMID 1586722.
- Dawson SJ, White LA (1992). "Treatment of Haemophilus aphrophilus endocarditis with ciprofloxacin.". J. Infect. 24 (3): 317–20. doi:10.1016/S0163-4453(05)80037-4. PMID 1602151.
- Kumble KD, Vishwanatha JK (1992). "Immunoelectron microscopic analysis of the intracellular distribution of primer recognition proteins, annexin 2 and phosphoglycerate kinase, in normal and transformed cells.". J. Cell. Sci. 99. ( Pt 4): 751–8. PMID 1837552.
- Maeda M, Yoshida A (1991). "Molecular defect of a phosphoglycerate kinase variant (PGK-Matsue) associated with hemolytic anemia: Leu----Pro substitution caused by T/A----C/G transition in exon 3.". Blood 77 (6): 1348–52. PMID 2001457.
- Jindal HK, Vishwanatha JK (1990). "Functional identity of a primer recognition protein as phosphoglycerate kinase.". J. Biol. Chem. 265 (12): 6540–3. PMID 2324090.
- Johnson P, Friedmann T (1990). "Limited bidirectional activity of two housekeeping gene promoters: human HPRT and PGK.". Gene 88 (2): 207–13. doi:10.1016/0378-1119(90)90033-N. PMID 2347494.
- Pfeifer GP, Steigerwald SD, Mueller PR, et al. (1989). "Genomic sequencing and methylation analysis by ligation mediated PCR.". Science 246 (4931): 810–3. doi:10.1126/science.2814502. PMID 2814502.
- Michelson AM, Blake CC, Evans ST, Orkin SH (1985). "Structure of the human phosphoglycerate kinase gene and the intron-mediated evolution and dispersal of the nucleotide-binding domain.". Proc. Natl. Acad. Sci. U.S.A. 82 (20): 6965–9. doi:10.1073/pnas.82.20.6965. PMC 391290. PMID 2995995.
- McCarrey JR, Thomas K (1987). "Human testis-specific PGK gene lacks introns and possesses characteristics of a processed gene.". Nature 326 (6112): 501–5. doi:10.1038/326501a0. PMID 3453121.
- Fujii H, Yoshida A (1981). "Molecular abnormality of phosphoglycerate kinase-Uppsala associated with chronic nonspherocytic hemolytic anemia.". Proc. Natl. Acad. Sci. U.S.A. 77 (9): 5461–5. doi:10.1073/pnas.77.9.5461. PMC 350080. PMID 6933565.
- Fujii H, Chen SH, Akatsuka J, et al. (1981). "Use of cultured lymphoblastoid cells for the study of abnormal enzymes: molecular abnormality of a phosphoglycerate kinase variant associated with hemolytic anemia.". Proc. Natl. Acad. Sci. U.S.A. 78 (4): 2587–90. doi:10.1073/pnas.78.4.2587. PMC 319394. PMID 6941312.
- Huang IY, Welch CD, Yoshida A (1980). "Complete amino acid sequence of human phosphoglycerate kinase. Cyanogen bromide peptides and complete amino acid sequence.". J. Biol. Chem. 255 (13): 6412–20. PMID 7391027.
- Fujii H, Krietsch WK, Yoshida A (1980). "A single amino acid substitution (Asp leads to Asn) in a phosphoglycerate kinase variant (PGK München) associated with enzyme deficiency.". J. Biol. Chem. 255 (13): 6421–3. PMID 7391028.
- Huang IY, Fujii H, Yoshida A (1981). "Structure and function of normal and variant human phosphoglycerate kinase.". Hemoglobin 4 (5-6): 601–9. doi:10.3109/03630268008997730. PMID 7440217.
- Kato S, Sekine S, Oh SW, et al. (1995). "Construction of a human full-length cDNA bank.". Gene 150 (2): 243–50. doi:10.1016/0378-1119(94)90433-2. PMID 7821789.
- Hershkovitz M, Riggs AD (1995). "Metaphase chromosome analysis by ligation-mediated PCR: heritable chromatin structure and a comparison of active and inactive X chromosomes.". Proc. Natl. Acad. Sci. U.S.A. 92 (6): 2379–83. doi:10.1073/pnas.92.6.2379. PMC 42487. PMID 7892275.
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