PEX26
From Wikipedia, the free encyclopedia
| Peroxisomal biogenesis factor 26 | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||
| Symbols | PEX26; PBD7A; PBD7B; PEX26M1T; Pex26pM1T | ||||||||||||
| External IDs | OMIM: 608666 MGI: 1921293 HomoloGene: 9922 GeneCards: PEX26 Gene | ||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 55670 | 74043 | |||||||||||
| Ensembl | ENSG00000215193 | ENSMUSG00000067825 | |||||||||||
| UniProt | Q7Z412 | Q8BGI5 | |||||||||||
| RefSeq (mRNA) | NM_001127649 | NM_028730 | |||||||||||
| RefSeq (protein) | NP_001121121 | NP_083006 | |||||||||||
| Location (UCSC) | Chr 22: 18.56 – 18.61 Mb | Chr 6: 121.18 – 121.2 Mb | |||||||||||
| PubMed search | |||||||||||||
Peroxisome assembly protein 26 is a protein that in humans is encoded by the PEX26 gene.[1][2][3]
Interactions
PEX26 has been shown to interact with PEX1,[1] PEX6[1] and SUFU.[4]
References
- ↑ 1.0 1.1 1.2 Matsumoto N, Tamura S, Fujiki Y (May 2003). "The pathogenic peroxin Pex26p recruits the Pex1p-Pex6p AAA ATPase complexes to peroxisomes". Nat Cell Biol 5 (5): 454–60. doi:10.1038/ncb982. PMID 12717447.
- ↑ Matsumoto N, Tamura S, Furuki S, Miyata N, Moser A, Shimozawa N, Moser HW, Suzuki Y, Kondo N, Fujiki Y (Jul 2003). "Mutations in Novel Peroxin Gene PEX26 That Cause Peroxisome-Biogenesis Disorders of Complementation Group 8 Provide a Genotype-Phenotype Correlation". Am J Hum Genet 73 (2): 233–46. doi:10.1086/377004. PMC 1180364. PMID 12851857.
- ↑ "Entrez Gene: PEX26 peroxisome biogenesis factor 26".
- ↑ Rual, Jean-François; Venkatesan Kavitha, Hao Tong, Hirozane-Kishikawa Tomoko, Dricot Amélie, Li Ning, Berriz Gabriel F, Gibbons Francis D, Dreze Matija, Ayivi-Guedehoussou Nono, Klitgord Niels, Simon Christophe, Boxem Mike, Milstein Stuart, Rosenberg Jennifer, Goldberg Debra S, Zhang Lan V, Wong Sharyl L, Franklin Giovanni, Li Siming, Albala Joanna S, Lim Janghoo, Fraughton Carlene, Llamosas Estelle, Cevik Sebiha, Bex Camille, Lamesch Philippe, Sikorski Robert S, Vandenhaute Jean, Zoghbi Huda Y, Smolyar Alex, Bosak Stephanie, Sequerra Reynaldo, Doucette-Stamm Lynn, Cusick Michael E, Hill David E, Roth Frederick P, Vidal Marc (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature (England) 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
Further reading
- Dunham I, Shimizu N, Roe BA et al. (1999). "The DNA sequence of human chromosome 22". Nature 402 (6761): 489–95. doi:10.1038/990031. PMID 10591208.
- Strausberg RL, Feingold EA, Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Ota T, Suzuki Y, Nishikawa T et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Collins JE, Wright CL, Edwards CA et al. (2005). "A genome annotation-driven approach to cloning the human ORFeome". Genome Biol. 5 (10): R84. doi:10.1186/gb-2004-5-10-r84. PMC 545604. PMID 15461802.
- Gerhard DS, Wagner L, Feingold EA et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Fransen M, Vastiau I, Brees C et al. (2005). "Analysis of human Pex19p's domain structure by pentapeptide scanning mutagenesis". J. Mol. Biol. 346 (5): 1275–86. doi:10.1016/j.jmb.2005.01.013. PMID 15713480.
- Weller S, Cajigas I, Morrell J et al. (2005). "Alternative Splicing Suggests Extended Function of PEX26 in Peroxisome Biogenesis". Am. J. Hum. Genet. 76 (6): 987–1007. doi:10.1086/430637. PMC 1196456. PMID 15858711.
- Rual JF, Venkatesan K, Hao T et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
- Furuki S, Tamura S, Matsumoto N et al. (2006). "Mutations in the peroxin Pex26p responsible for peroxisome biogenesis disorders of complementation group 8 impair its stability, peroxisomal localization, and interaction with the Pex1p x Pex6p complex". J. Biol. Chem. 281 (3): 1317–23. doi:10.1074/jbc.M510044200. PMID 16257970.
- Halbach A, Landgraf C, Lorenzen S et al. (2006). "Targeting of the tail-anchored peroxisomal membrane proteins PEX26 and PEX15 occurs through C-terminal PEX19-binding sites". J. Cell. Sci. 119 (Pt 12): 2508–17. doi:10.1242/jcs.02979. PMID 16763195.
- Tamura S, Yasutake S, Matsumoto N, Fujiki Y (2006). "Dynamic and functional assembly of the AAA peroxins, Pex1p and Pex6p, and their membrane receptor Pex26p". J. Biol. Chem. 281 (38): 27693–704. doi:10.1074/jbc.M605159200. PMID 16854980.
External links
- GeneReviews/NCBI/NIH/UW entry on Peroxisome Biogenesis Disorders, Zellweger Syndrome Spectrum
- OMIM entries on Peroxisome Biogenesis Disorders, Zellweger Syndrome Spectrum
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