Omphalotus subilludens
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| Omphalotus subilludens | |
|---|---|
| Scientific classification | |
| Kingdom: | Fungi |
| Division: | Basidiomycota |
| Class: | Agaricomycetes |
| Order: | Agaricales |
| Family: | Marasmiaceae |
| Genus: | Omphalotus |
| Species: | O. subilludens |
| Binomial name | |
| Omphalotus subilludens (Murrill) H.E. Bigelow 1982 | |
| Synonyms | |
|
Clitocybe subilludens (Murrill) Murrill 1945[1]
| |
Omphalotus subilludens is a fungus species in the genus Omphalotus.
Atromentin and thelephoric acid are chemical compounds found in cultures of C. subilludens.[2] Atromentin is an effective anticoagulant, and similar in biological activity to the well-known anticoagulant heparin.[3] Atromentin also possesses antibacterial activity, inhibiting the enzyme enoyl-acyl carrier protein reductase (essential for the biosynthesis of fatty acids) in the bacteria Streptococcus pneumoniae.[4]
It also produces illudoids.[5]
References
- ↑ Murrill, W.A., 1945, Quarterly Journal of the Florida Academy of Science 8(2): 198
- ↑ Sullivan, G.; Garrett, R. D.; Lenehan, R. F. (1971). "Occurrence of atromentin and thelephoric acid in cultures ofclitocybe subilludens". Journal of Pharmaceutical Sciences 60 (11): 1727–9. doi:10.1002/jps.2600601134. PMID 4332377.
- ↑ Khanna JM, Malone MH, Euler KL, Brady LR. (1965). "Atromentin – anticoagulant from Hydnellum diabolus". Journal of Pharmaceutical Science 54 (7): 1016–20. doi:10.1002/jps.2600540714. PMID 5862512.
- ↑ Zheng CJ, Sohn MJ, Kim WG. (2006). "Atromentin and leucomelone, the first inhibitors specific to enoyl-ACP reductase (FabK) of Streptococcus pneumoniae". Journal of Antibiotics 59 (12): 808–12. doi:10.1038/ja.2006.108. PMID 17323650.
- ↑ Illudoids from Omphalotus olivascens and Clitocybe subilludens. Nair M. S. R., Carey S. T. and Rogerson C. T., Mycologia, 1983, vol. 75, no5, pages 920-922, INIST:9415717
External links
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