Nucleoporin
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| Nucleoporin | |||||||||
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| Identifiers | |||||||||
| Symbol | Nucleoporin | ||||||||
| Pfam | PF03177 | ||||||||
| InterPro | IPR004870 | ||||||||
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The nucleoporins are a family of proteins which are the constituent building blocks of the nuclear pore complex.[1] The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the cell nucleus and the cytoplasm. Nucleoporins, a family of 50 to 100 proteins, are the main components of the nuclear pore complex in eukaryotic cells. Nuclear pores in turn allow the transport of water-soluble molecules across the nuclear envelope.
The proteins involved are named for their molecular weight (in kilo Daltons), and include the following:
- NUP35, NUP37, NUP43, NUP50
- NUP54, NUP62, NUP85, NUP88, NUP93, NUP98
- NUP107, NUP133, NUP153, NUP155, NUP160, NUP188
- NUP205, NUP210, NUP214
References
- ↑ Doye V, Hurt E (June 1997). "From nucleoporins to nuclear pore complexes". Curr. Opin. Cell Biol. 9 (3): 401–11. doi:10.1016/S0955-0674(97)80014-2. PMID 9159086.
External links
- Nucleoporin at the US National Library of Medicine Medical Subject Headings (MeSH)
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