Notholaenic acid

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Notholaenic acid
Chemical structure of notholaenic acid
Identifiers
CAS number 72578-97-3
PubChem 3085829
Jmol-3D images Image 1
Properties
Molecular formula C17H18O5
Molar mass 302.32 g mol−1
Melting point 149–150 °C
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Notholaenic acid is a dihydrostilbenoid found in the farina of some ferns of the genus Notholaena.[1] It has been shown to have anti-HSV-1 activity at high concentrations in vitro.[2] It was artificially synthesized, starting from 3-benzyloxy-5-methoxybenzyl alcohol, in 1985.[3]

References

  1. Wollenweber, Eckhard; Favre-Bonvin, Jean (1979). "Novel dihydrostilbene from fronds of Notholaena dealbata and Notholaena limitanea". Phytochemistry 18 (7): 1243–1244. doi:10.1016/0031-9422(79)80153-3. 
  2. Rinehart, Kenneth L.; Tom G. Holt, Nancy L. Fregeau, Paul A. Keifer, George Robert Wilson, Thomas J. Perun Jr., Ryuichi Sakai, Anthony G. Thompson, Justin G. Stroh, Lois S. Shield, David S. Seigler, Li H. Li, David G. Martin, Cornelis J. P. Grimmelikhuijzen, Gerd Gäde (July–Aug 1990). "Bioactive Compounds from Aquatic and Terrestrial Sources". Journal of Natural Products 53: 771–792. doi:10.1021/np50070a001. Retrieved 29 April 2012. 
  3. El-Feraly, Farouk S.; Cheatham, Steve F.; McChesney, James D. (1985). "Total Synthesis of Notholaenic Acid". Journal of Natural Products 48 (2): 293–298. doi:10.1021/np50038a015. 
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