Neticonazole

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Neticonazole

Systematic (IUPAC) name
1-{(E)-2-(methylthio)-1-[2-(pentyloxy)phenyl]vinyl}-1H-imidazole
Clinical data
AHFS/Drugs.com	International Drug Names
Legal status	?
Identifiers

ATC code	None
PubChem	CID 5282433
UNII	KVL61ZF9UO^Y
Chemical data
Formula	C₁₇H₂₂N₂O S
Mol. mass	302.43 g/mol
Y (what is this?) (verify)

Neticonazole (INN) is an imidazole antifungal for the treatment of fungal skin infections.^[1]^[2]

Neticonazole is only approved for use in Japan. It is sold as a topical ointment under the tradename Atolant.

References

↑ Nimura K, Niwano Y, Ishiduka S, Fukumoto R (August 2001). "Comparison of in vitro antifungal activities of topical antimycotics launched in 1990s in Japan". Int. J. Antimicrob. Agents 18 (2): 173–8. doi:10.1016/S0924-8579(01)00365-X. PMID 11516941.
↑ Tsuboi R, Matsumoto T, Ogawa H (May 1996). "Hyperkeratotic chronic tinea pedis treated with neticonazole cream. Neticonazole Study Group". Int. J. Dermatol. 35 (5): 371–3. doi:10.1111/j.1365-4362.1996.tb03644.x. PMID 8734665.

Wall/
membrane

Ergosterol
inhibitors

Imidazoles	topical: Bifonazole Butoconazole Clomidazole Clotrimazole^#, Croconazole Econazole Fenticonazole Ketoconazole Isoconazole Miconazole^#, Neticonazole Omoconazole Oxiconazole Sertaconazole Sulconazole Tioconazole

Triazoles	topical: (Fluconazole^#, Fosfluconazole Terconazole) systemic: (Fluconazole Hexaconazole Isavuconazole^†, Itraconazole Posaconazole Voriconazole) unknown: (Albaconazole)

Thiazoles	topical: (Abafungin)

β-glucan synthase
inhibitors

Intracellular

Pyrimidine analogues/ Thymidylate synthase inhibitors	Flucytosine^#

Mitotic inhibitors	Griseofulvin^#

Others

fung, clas

fung

drug (fung)

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