Nervonic acid

Nervonic acid[1]
IUPAC name (Z)-Tetracos-15-enoic acid
Other names cis-15-Tetracosenoic acid 24:1 cis, delta 15 or 24:1 omega 9
Identifiers
CAS number	506-37-6 N
PubChem	5281120
ChemSpider	4444565 Y
KEGG	C08323 Y
ChEBI	CHEBI:44247 Y
ChEMBL	CHEMBL1173379 Y
Jmol-3D images	Image 1
SMILES O=C(O)CCCCCCCCCCCCC\C=C/CCCCCCCC
InChI InChI=1S/C24H46O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24(25)26/h9-10H,2-8,11-23H2,1H3,(H,25,26)/b10-9- Y Key: GWHCXVQVJPWHRF-KTKRTIGZSA-N Y InChI=1/C24H46O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24(25)26/h9-10H,2-8,11-23H2,1H3,(H,25,26)/b10-9- Key: GWHCXVQVJPWHRF-KTKRTIGZBL
Properties
Molecular formula	C24H46O2
Molar mass	366.62 g/mol
Melting point	42–43 °C
N (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Nervonic acid is a monounsaturated omega-9 fatty acid. Nervonic acid has been identified as important in the biosynthesis of nerve cell myelin.^[2] It is found in the sphingolipids of white matter in human brain.

Nervonic acid is used in the treatment of disorders involving demyelination, such as adrenoleukodystrophy and multiple sclerosis where there is a decreased level of nervonic acid in sphingolipids.^[3]

Dietary sources

Nervonic acid is abundant in King Salmon (Chinook) with 140 mg/100g, yellow mustard seed 83 mg/100g, flaxseed 64 mg/100g, Sockeye salmon 40 mg/100g, sesame seed 35 mg/100g, and macademia nuts 18 mg/100g ^[4]

References

Additional references

• Appelqvist (1976) Lipids in Cruciferae. In: Vaughan JG, Macleod AJ (Eds), The biology and the Chemistry of Cruciferae. Academic Press, London, UK, pp. 221-277.
• Sargent JR, Coupland K, Wilson R (1994). Nervonic Acid and Demyelinating Disease. Medical Hypothesese 42, pp. 237-242.