Neoxanthin synthase

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Neoxanthin synthase
Identifiers
EC number 5.3.99.9
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

In enzymology, a neoxanthin synthase (EC 5.3.99.9) is an enzyme that catalyzes the chemical reaction:

violaxanthin \rightleftharpoons neoxanthin

Hence, this enzyme has one substrate, violaxanthin, and one product, neoxanthin.

This enzyme belongs to the family of isomerases, specifically a class of other intramolecular oxidoreductases. The systematic name of this enzyme class is violaxanthin---neoxanthin isomerase (epoxide-opening). This enzyme is also called NSY. This enzyme participates in carotenoid biosynthesis - general.

References

    • Beyer P; Hugueney, P; Schledz, M; Welsch, R; Frohnmeyer, H; Laule, O; Beyer, P (2000). "Identification of a novel gene coding for neoxanthin synthase from Solanum tuberosum". FEBS. Lett. 485 (2–3): 16872. doi:10.1016/S0014-5793(00)02193-1. PMID 11094161. 
    • Bouvier F, D'harlingue A, Backhaus RA, Kumagai MH, Camara B (2000). "Identification of neoxanthin synthase as a carotenoid cyclase paralog". Eur. J. Biochem. 267 (21): 634652. doi:10.1046/j.1432-1327.2000.01722.x. PMID 11029576. 
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