NDUFA2
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| NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa | |||||||||||||
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 PDB rendering based on 1s3a. | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | NDUFA2; B8; CD14; CIB8 | ||||||||||||
| External IDs | OMIM: 602137 MGI: 1343103 HomoloGene: 37628 GeneCards: NDUFA2 Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
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| More reference expression data | |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 4695 | 17991 | |||||||||||
| Ensembl | ENSG00000131495 | ENSMUSG00000014294 | |||||||||||
| UniProt | O43678 | Q9CQ75 | |||||||||||
| RefSeq (mRNA) | NM_001185012 | NM_010885 | |||||||||||
| RefSeq (protein) | NP_001171941 | NP_035015 | |||||||||||
| Location (UCSC) | Chr 5: 140.02 – 140.03 Mb | Chr 18: 36.74 – 36.74 Mb | |||||||||||
| PubMed search | |||||||||||||
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 is an enzyme that in humans is encoded by the NDUFA2 gene.[1][2][3]
References
- ↑ Ton C, Hwang DM, Dempsey AA, Liew CC (Jan 1998). "Identification and primary structure of five human NADH-ubiquinone oxidoreductase subunits". Biochem Biophys Res Commun 241 (2): 589–94. doi:10.1006/bbrc.1997.7707. PMID 9425316.
- ↑ Emahazion T, Brookes AJ (Nov 1998). "Mapping of the NDUFA2, NDUFA6, NDUFA7, NDUFB8, and NDUFS8 electron transport chain genes by intron based radiation hybrid mapping". Cytogenet Cell Genet 82 (1-2): 114. doi:10.1159/000015081. PMID 9763676.
- ↑ "Entrez Gene: NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa".
Further reading
- Walker JE, Arizmendi JM, Dupuis A, et al. (1992). "Sequences of 20 subunits of NADH:ubiquinone oxidoreductase from bovine heart mitochondria. Application of a novel strategy for sequencing proteins using the polymerase chain reaction.". J. Mol. Biol. 226 (4): 1051–72. doi:10.1016/0022-2836(92)91052-Q. PMID 1518044.
- Dunbar DR, Shibasaki Y, Dobbie L, et al. (1997). "In situ hybridisation mapping of genomic clones for five human respiratory chain complex I genes.". Cytogenet. Cell Genet. 78 (1): 21–4. doi:10.1159/000134618. PMID 9345899.
- Loeffen JL, Triepels RH, van den Heuvel LP, et al. (1999). "cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed.". Biochem. Biophys. Res. Commun. 253 (2): 415–22. doi:10.1006/bbrc.1998.9786. PMID 9878551.
- Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Brockmann C, Diehl A, Rehbein K, et al. (2005). "The oxidized subunit B8 from human complex I adopts a thioredoxin fold.". Structure 12 (9): 1645–54. doi:10.1016/j.str.2004.06.021. PMID 15341729.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Vogel RO, Dieteren CE, van den Heuvel LP, et al. (2007). "Identification of mitochondrial complex I assembly intermediates by tracing tagged NDUFS3 demonstrates the entry point of mitochondrial subunits.". J. Biol. Chem. 282 (10): 7582–90. doi:10.1074/jbc.M609410200. PMID 17209039.
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