N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline
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| N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline[1] | ||
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| IUPAC name 2-Ethoxy-2H-quinoline-1-carboxylic acid ethyl ester | ||
| Other names Ethyl 1,2-dihydro-2-ethoxyquinoline-1-carboxylate | ||
| Identifiers | ||
| Abbreviations | EEDQ | |
| CAS number | 16357-59-8 | |
| PubChem | 27833 | |
| Jmol-3D images | Image 1 | |
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| Properties | ||
| Molecular formula | C14H17NO3 | |
| Molar mass | 247.29 g/mol | |
| Melting point | 62-67 °C | |
 (verify) (what is: / ?)Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa) | ||
| Infobox references | ||
N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ) is an irreversible dopamine-receptor antagonist.[2]
EEDQ is also a highly specific reagent for carboxyl groups. It enables the coupling of acylamino acids with amino acid esters in high yield and without racemization.[3]
References
- ↑ 2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline at Sigma-Aldrich
- ↑ Neuroscience Letters 1992, 137(2), p.265
- ↑ https://www.bachem.com/bachem/bachem/joust/index.cfm?idland=223
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