Morin (flavonol)

Morin
IUPAC name 2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-one
Other names Aurantica Al-Morin Morin hydrate Calico Yellow Toxylon pomiferum Bois d'arc Osage orange extract
Identifiers
CAS number	654055-01-3
PubChem	5281670
ChemSpider	4444989 Y
KEGG	C10105 Y
ChEBI	CHEBI:75092
ChEMBL	CHEMBL28626 Y
IUPHAR ligand	411
Jmol-3D images	Image 1
SMILES O=C1c3c(O/C(=C1/O)c2ccc(O)cc2O)cc(O)cc3O
InChI InChI=1S/C15H10O7/c16-6-1-2-8(9(18)3-6)15-14(21)13(20)12-10(19)4-7(17)5-11(12)22-15/h1-5,16-19,21H Y Key: YXOLAZRVSSWPPT-UHFFFAOYSA-N Y InChI=1/C15H10O7/c16-6-1-2-8(9(18)3-6)15-14(21)13(20)12-10(19)4-7(17)5-11(12)22-15/h1-5,16-19,21H Key: YXOLAZRVSSWPPT-UHFFFAOYAH
Properties
Molecular formula	C15H10O7
Molar mass	302.2357 g/mol
Density	1.799 g/mL
Y (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Morin is a chemical compound. It is a yellow color substance that can be isolated from Maclura pomifera (Osage orange), Maclura tinctoria (old fustic) and from leaves of Psidium guajava (common guava).^[1] In a preclinical study it was found to be the most potent flavonoid inhibitor of fatty acid synthase tested with an IC₅₀ of 2.33±0.09μM.^[2]

Morin can be used to test for the presence of aluminium or tin in a solution, since it forms characteristically fluorescent coordination complexes with them.

Glycosides

• Morin-3-O-arabinoside^[1]
• Morin-3-O-lyxoside^[1]

References

1. ↑ 1.0 1.1 1.2 Bacteriostatic effect of flavonoids isolated from leaves of Psidium guajava on fish pathogens. Rattanachaikunsopon Pongsak and Phumkhachorn Parichat, INIST:19087798
2. ↑ Tian, WX (February 2006). "Inhibition of Fatty Acid Synthase by Polyphenols". Current Medicinal Chemistry 13 (8): 967–977. doi:10.2174/092986706776361012. PMID 16611078.