Methyl hydroxychalcone

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Methyl hydroxychalcone
Chemical structure of methyl hydroxychalcone
IUPAC name

(E)-3-(3-hydroxyphenyl)-1-(3-methylphenyl)prop-2-en-1-one

Other names

MCHP
3'-Methyl-3-hydroxychalcone

Identifiers
CAS number 153976-41-1 YesY
PubChem 6440383
Jmol-3D images Image 1
Properties
Molecular formula C16H14O2
Molar mass 238.28 g/mol
 YesY (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Methyl hydroxychalcone is a chalconoid found in cinnamon. It was thought to be an insulin mimetic, improving insulin response of diabetics.[1] It has since been determined that a flavonoid (cinnamtannin B1) is responsible for the insulin-like biological activity.[2]

See also

References

  1. ↑ Anderson; A; G (August 1, 2001). "A hydroxychalcone derived from cinnamon functions as a mimetic for insulin in 3T3-L1 adipocytes". J Am Coll Nutr. 20 (4): 327–36. PMID 11506060. Retrieved 2008-06-19.  More than one of |author1= and |last= specified (help)
  2. ↑ Anderson; Broadhurst, CL; Polansky, MM; Schmidt, WF; Khan, A; Flanagan, VP; Schoene, NW; Graves, DJ (January 2004). "Isolation and characterization of polyphenol type-A polymers from cinnamon with insulin-like biological activity". J Agric Food Chem. 52 (1): 65–70. doi:10.1021/jf034916b. PMID 14709014. 


Chalconoids and their glycosides
Chalconoids
Chalconoid glycosides
  • Carthamin
  • Marein
  • okanin 3,4,3′-trimethyl ether 4′-glucoside
  • okanin 4-methyl ether 4′-glucoside
  • okanin 4-methyl ether 4′-glucoside monoacetate
  • Okanin 3,4-dimethyl ether 4′-glucoside
Acetylated chalconoids
O-methylated chalconoids
  • Cardamomin
  • Okanin 3,4,3′,4′-tetramethyl ether
Flavokavains
Synthetic
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