Methanandamide
Methanandamide | |
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IUPAC name (5Z,8Z,11Z,14Z)-N-[(1R)-2-hydroxy-1-methylethyl]icosa-5,8,11,14-tetraenamide | |
Other names AM-356; Arachidonyl-1'-hydroxy-2'-propylamide | |
Identifiers | |
CAS number | 157182-49-5 |
PubChem | 6321351 |
ChemSpider | 4881984 |
ChEMBL | CHEMBL120526 |
Jmol-3D images | {{#if:O=C(N[C@H](C)CO)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC|Image 1 |
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Properties | |
Molecular formula | C23H39NO2 |
Molar mass | 361.56 g mol−1 |
(verify) (what is: / ?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa) | |
Infobox references | |
Methanandamide (AM-356) is a synthetically created stable chiral analog of anandamide.[1] Its effects have been observed to act on the cannabinoid receptors (specifically on CB1 receptors, which are part of the central nervous system) found in different organisms such as mammals, fish, and certain invertebrates (e.g. Hydra).
References
- ↑ Abadji, V, et al. (1994). "(R)-methanandamide: A chiral novel anandamide possessing higher potency and metabolic stability". Journal of Medical Chemistry 37 (12): 1889–93. doi:10.1021/jm00038a020. PMID 8021930.