Metahexamide

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Metahexamide

IUPAC name 1-(3-amino-4-methylphenyl)sulfonyl-3-cyclohexylurea
Identifiers
CAS number	565-33-3^Y
PubChem	11259
	ChEMBL	CHEMBL507419^N
ATC code	A10BB10
Jmol-3D images	Image 1
SMILES CC1=C(C=C(C=C1)S(=O)(=O)NC(=O)NC2CCCCC2)N
Properties
Molecular formula	C₁₄H₂₁N₃O₃S
Molar mass	311.4 g/mol
N (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Metahexamide (INN) is an anti-diabetic drug from the group of sulfonylureas. It was first described in 1959.^[1]

References

↑ Moss JM, Delawter D (September 1959). "Metahexamide in diabetes therapy". Ann NY Acad Sci 82 (2): 614–7. doi:10.1111/j.1749-6632.1959.tb44940.x. PMID 14424617.

Oral anti-diabetic drugs and Insulin analogs (A10)

Sensitizers

Biguanides	Metformin^# Buformin^‡ Phenformin^‡

TZDs/"glitazones" (PPAR)	Pioglitazone Rivoglitazone^† Rosiglitazone Troglitazone^‡

Dual PPAR agonists	Aleglitazar^† Muraglitazar^§ Saroglitazar Tesaglitazar^§

Secretagogues

Sulfonylureas	1st generation: Acetohexamide Carbutamide Chlorpropamide Metahexamide Tolbutamide Tolazamide 2nd generation: Glibenclamide (Glyburide)^# Glibornuride Glipizide Gliquidone Glisoxepide Glyclopyramide Glimepiride Gliclazide

Meglitinides/"glinides"	Nateglinide Repaglinide Mitiglinide

Analogs/other insulins

Other

Alpha-glucosidase inhibitors	Acarbose Miglitol Voglibose

Amylin analog	Pramlintide

SGLT2 inhibitors	Canagliflozin Dapagliflozin Empagliflozin^† Remogliflozin^§ Sergliflozin^§ Tofogliflozin^†

Other	Bromocriptine Benfluorex^‡ Tolrestat^‡

anat/phys/devp/horm

noco (d)/cong/tumr, sysi/epon

proc, drug (A10/H1/H2/H3/H5)

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