Marinobufagenin

Marinobufagenin
Other names Marinobufagin, Marinobufagenin
Identifiers
CAS number	470-42-8
PubChem	11969465
	Jmol-3D images	{{#if:C[C@]12CC[C@@H](C[C@]1(CCC3C2CC[C@]4([C@]35[C@H](O5)C[C@@H]4C6=COC(=O)C=C6)C)O)O|Image 1
SMILES C[C@]12CC[C@@H](C[C@]1(CCC3C2CC[C@]4([C@]35[C@H](O5)C[C@@H]4C6=COC(=O)C=C6)C)O)O
Properties
Molecular formula	C24H32O5
Molar mass	400.51 g mol−1
Hazards
Main hazards	Toxic
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Infobox references

Marinobufagenin (marinobufagin) is a cardiotonic bufadienolide steroid secreted by the toad Bufo rubescens^[1] and other related species such as Bufo marinus. It is a vasoconstrictor with effects similar to digitalis.^[2]

References

1. ↑ Cunha Filho, GA; Schwartz, CA; Resck, IS; Murta, MM; Lemos, SS; Castro, MS; Kyaw, C; Pires Jr, OR et al. (2005). "Antimicrobial activity of the bufadienolides marinobufagin and telocinobufagin isolated as major components from skin secretion of the toad Bufo rubescens". Toxicon : official journal of the International Society on Toxinology 45 (6): 777–82. doi:10.1016/j.toxicon.2005.01.017. PMID 15804527.  |displayauthors= suggested (help)
2. ↑ Fedorova, OV; Talan, MI; Agalakova, NI; Lakatta, EG; Bagrov, AY (2002). "Endogenous ligand of alpha(1) sodium pump, marinobufagenin, is a novel mediator of sodium chloride--dependent hypertension". Circulation 105 (9): 1122–7. PMID 11877366.