MYST4
From Wikipedia, the free encyclopedia
Histone acetyltransferase MYST4 is an enzyme that in humans is encoded by the MYST4 gene.[1][2][3]
Interactions
MYST4 has been shown to interact with RUNX2.[4]
Young Simpson syndrome
It has been demonstrated that de novo mutations in the gene MYST4 causes the Young Simpson syndrome and genitopatellar syndrome.[5][6][7] [8]
References
- ↑ Nagase T, Ishikawa K, Nakajima D, Ohira M, Seki N, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Sep 1997). "Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res 4 (2): 141–50. doi:10.1093/dnares/4.2.141. PMID 9205841.
- ↑ Champagne N, Bertos NR, Pelletier N, Wang AH, Vezmar M, Yang Y, Heng HH, Yang XJ (Nov 1999). "Identification of a human histone acetyltransferase related to monocytic leukemia zinc finger protein". J Biol Chem 274 (40): 28528–36. doi:10.1074/jbc.274.40.28528. PMID 10497217.
- ↑ "Entrez Gene: MYST4 MYST histone acetyltransferase (monocytic leukemia) 4".
- ↑ Pelletier, Nadine; Champagne Nathalie, Stifani Stefano, Yang Xiang-Jiao (Apr 2002). "MOZ and MORF histone acetyltransferases interact with the Runt-domain transcription factor Runx2". Oncogene (England) 21 (17): 2729–40. doi:10.1038/sj.onc.1205367. ISSN 0950-9232. PMID 11965546.
- ↑ Campeau, PM; Kim, JC, Lu, JT, Schwartzentruber, JA, Abdul-Rahman, OA, Schlaubitz, S, Murdock, DM, Jiang, MM, Lammer, EJ, Enns, GM, Rhead, WJ, Rowland, J, Robertson, SP, Cormier-Daire, V, Bainbridge, MN, Yang, XJ, Gingras, MC, Gibbs, RA, Rosenblatt, DS, Majewski, J, Lee, BH (Jan 18, 2012). "Mutations in KAT6B, Encoding a Histone Acetyltransferase, Cause Genitopatellar Syndrome.". American Journal of Human Genetics 90 (2): 282–9. doi:10.1016/j.ajhg.2011.11.023. PMID 22265014.
- ↑ Clayton-Smith, Jill; O'Sullivan James, Daly Sarah, Bhaskar Sanjeev, Day Ruth, Anderson Beverley, Voss Anne K, Thomas Tim, Biesecker Leslie G, Smith Philip, Fryer Alan, Chandler Kate E, Kerr Bronwyn, Tassabehji May, Lynch Sally-Ann, Krajewska-Walasek Malgorzata, McKee Shane, Smith Janine, Sweeney Elizabeth, Mansour Sahar, Mohammed Shehla, Donnai Dian, Black Graeme (Nov 2011). "Whole-Exome-Sequencing Identifies Mutations in Histone Acetyltransferase Gene KAT6B in Individuals with the Say-Barber-Biesecker Variant of Ohdo Syndrome". Am. J. Hum. Genet. (United States) 89 (5): 675–81. doi:10.1016/j.ajhg.2011.10.008. PMID 22077973.
- ↑ Campeau, Philippe M; Kim Jaeseung C, Lu James T, Schwartzentruber Jeremy A, Abdul-Rahman Omar A, Schlaubitz Silke, Murdock David M, Jiang Ming-Ming, Lammer Edward J, Enns Gregory M, Rhead William J, Rowland Jon, Robertson Stephen P, Cormier-Daire Valérie, Bainbridge Matthew N, Yang Xiang-Jiao, Gingras Marie-Claude, Gibbs Richard A, Rosenblatt David S, Majewski Jacek, Lee Brendan H (Jan 2012). "Mutations in KAT6B, Encoding a Histone Acetyltransferase, Cause Genitopatellar Syndrome". American journal of human genetics (in ENG) 90 (2): 282–9. doi:10.1016/j.ajhg.2011.11.023. PMID 22265014.
- ↑ Campeau, PM; Lu, JT; Dawson, BC; Fokkema, IF; Robertson, SP; Gibbs, RA; Lee, BH (Jun 19, 2012). "The KAT6B-related disorders Genitopatellar syndrome and Ohdo/SBBYS syndrome have distinct clinical features reflecting distinct molecular mechanisms.". Human Mutation 33 (11): 1520–5. doi:10.1002/humu.22141. PMID 22715153.
Further reading
- Pena AN, Pereira-Smith OM (2007). "The role of the MORF/MRG family of genes in cell growth, differentiation, DNA repair, and thereby aging". Ann. N. Y. Acad. Sci. 1100: 299–305. doi:10.1196/annals.1395.031. PMID 17460191.
- Nakajima D, Okazaki N, Yamakawa H, et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Res. 9 (3): 99–106. doi:10.1093/dnares/9.3.99. PMID 12168954.
- Topper M, Luo Y, Zhadina M, et al. (2007). "Posttranslational Acetylation of the Human Immunodeficiency Virus Type 1 Integrase Carboxyl-Terminal Domain Is Dispensable for Viral Replication". J. Virol. 81 (6): 3012–7. doi:10.1128/JVI.02257-06. PMC 1865993. PMID 17182677.
- Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
- Cereseto A, Manganaro L, Gutierrez MI, et al. (2005). "Acetylation of HIV-1 integrase by p300 regulates viral integration". EMBO J. 24 (17): 3070–81. doi:10.1038/sj.emboj.7600770. PMC 1201351. PMID 16096645.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
- Liu C, Lu J, Tan J, et al. (2005). "Human interleukin-5 expression is synergistically regulated by histone acetyltransferase CBP/p300 and transcription factors C/EBP, NF-AT and AP-1". Cytokine 27 (4–5): 93–100. doi:10.1016/j.cyto.2004.02.003. PMID 15271374.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Pelletier N, Champagne N, Stifani S, Yang XJ (2002). "MOZ and MORF histone acetyltransferases interact with the Runt-domain transcription factor Runx2". Oncogene 21 (17): 2729–40. doi:10.1038/sj.onc.1205367. PMID 11965546.
- Panagopoulos I, Fioretos T, Isaksson M, et al. (2001). "Fusion of the MORF and CBP genes in acute myeloid leukemia with the t(10;16)(q22;p13)". Hum. Mol. Genet. 10 (4): 395–404. doi:10.1093/hmg/10.4.395. PMID 11157802.
External links
- MYST4 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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