MYST1
From Wikipedia, the free encyclopedia
Probable histone acetyltransferase MYST1 is an enzyme that in humans is encoded by the MYST1 gene.[1][2]
The MYST family of histone acetyltransferases, which includes MYST1, is named for the founding members MOZ (MYST3; MIM 601408), yeast YBF2 and SAS2, and TIP60 (HTATIP; MIM 601409). All members of this family contain a MYST region of about 240 amino acids with a canonical acetyl-CoA-binding site and a C2HC-type zinc finger motif. Most MYST proteins also have a chromodomain involved in protein-protein interactions and targeting transcriptional regulators to chromatin (Neal et al., 2000).[supplied by OMIM][2]
Interactions
MYST1 has been shown to interact with MORF4L1.[3]
References
- ↑ Neal KC, Pannuti A, Smith ER, Lucchesi JC (May 2000). "A new human member of the MYST family of histone acetyl transferases with high sequence similarity to Drosophila MOF". Biochim Biophys Acta 1490 (1–2): 170–4. PMID 10786633.
- ↑ 2.0 2.1 "Entrez Gene: MYST1 MYST histone acetyltransferase 1".
- ↑ Pardo, Patricia S; Leung James K, Lucchesi John C, Pereira-Smith Olivia M (Dec 2002). "MRG15, a novel chromodomain protein, is present in two distinct multiprotein complexes involved in transcriptional activation". J. Biol. Chem. (United States) 277 (52): 50860–6. doi:10.1074/jbc.M203839200. ISSN 0021-9258. PMID 12397079.
Further reading
- Rea S, Xouri G, Akhtar A (2007). "Males absent on the first (MOF): from flies to humans". Oncogene 26 (37): 5385–94. doi:10.1038/sj.onc.1210607. PMID 17694080.
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- Kitabayashi I, Aikawa Y, Nguyen LA, et al. (2002). "Activation of AML1-mediated transcription by MOZ and inhibition by the MOZ–CBP fusion protein". EMBO J. 20 (24): 7184–96. doi:10.1093/emboj/20.24.7184. PMC 125775. PMID 11742995.
- Pelletier N, Champagne N, Stifani S, Yang XJ (2002). "MOZ and MORF histone acetyltransferases interact with the Runt-domain transcription factor Runx2". Oncogene 21 (17): 2729–40. doi:10.1038/sj.onc.1205367. PMID 11965546.
- Pardo PS, Leung JK, Lucchesi JC, Pereira-Smith OM (2003). "MRG15, a novel chromodomain protein, is present in two distinct multiprotein complexes involved in transcriptional activation". J. Biol. Chem. 277 (52): 50860–6. doi:10.1074/jbc.M203839200. PMID 12397079.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Wan D, Gong Y, Qin W, et al. (2004). "Large-scale cDNA transfection screening for genes related to cancer development and progression". Proc. Natl. Acad. Sci. U.S.A. 101 (44): 15724–9. doi:10.1073/pnas.0404089101. PMC 524842. PMID 15498874.
- Gupta A, Sharma GG, Young CS, et al. (2005). "Involvement of Human MOF in ATM Function". Mol. Cell. Biol. 25 (12): 5292–305. doi:10.1128/MCB.25.12.5292-5305.2005. PMC 1140595. PMID 15923642.
- Dou Y, Milne TA, Tackett AJ, et al. (2005). "Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF". Cell 121 (6): 873–85. doi:10.1016/j.cell.2005.04.031. PMID 15960975.
- Taipale M, Rea S, Richter K, et al. (2005). "hMOF Histone Acetyltransferase Is Required for Histone H4 Lysine 16 Acetylation in Mammalian Cells". Mol. Cell. Biol. 25 (15): 6798–810. doi:10.1128/MCB.25.15.6798-6810.2005. PMC 1190338. PMID 16024812.
- Cereseto A, Manganaro L, Gutierrez MI, et al. (2005). "Acetylation of HIV-1 integrase by p300 regulates viral integration". EMBO J. 24 (17): 3070–81. doi:10.1038/sj.emboj.7600770. PMC 1201351. PMID 16096645.
- Smith ER, Cayrou C, Huang R, et al. (2005). "A Human Protein Complex Homologous to the Drosophila MSL Complex Is Responsible for the Majority of Histone H4 Acetylation at Lysine 16". Mol. Cell. Biol. 25 (21): 9175–88. doi:10.1128/MCB.25.21.9175-9188.2005. PMC 1265810. PMID 16227571.
- Topper M, Luo Y, Zhadina M, et al. (2007). "Posttranslational Acetylation of the Human Immunodeficiency Virus Type 1 Integrase Carboxyl-Terminal Domain Is Dispensable for Viral Replication". J. Virol. 81 (6): 3012–7. doi:10.1128/JVI.02257-06. PMC 1865993. PMID 17182677.
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