MFRP
From Wikipedia, the free encyclopedia
| Membrane frizzled-related protein | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | MFRP; MCOP5; NNO2; RD6 | ||||||||||||
| External IDs | OMIM: 606227 HomoloGene: 12866 GeneCards: MFRP Gene | ||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 83552 | 259172 | |||||||||||
| Ensembl | ENSG00000223953 | ENSMUSG00000034739 | |||||||||||
| UniProt | Q9BY79 | Q8K480 | |||||||||||
| RefSeq (mRNA) | NM_031433 | NM_001190314 | |||||||||||
| RefSeq (protein) | NP_113621 | NP_001177243 | |||||||||||
| Location (UCSC) | Chr 11: 119.21 – 119.22 Mb | Chr 9: 44.1 – 44.11 Mb | |||||||||||
| PubMed search | |||||||||||||
Membrane frizzled-related protein is a protein that in humans is encoded by the MFRP gene.[1][2]
References
- ↑ Katoh M (Mar 2001). "Molecular cloning and characterization of MFRP, a novel gene encoding a membrane-type Frizzled-related protein". Biochem Biophys Res Commun 282 (1): 116–23. doi:10.1006/bbrc.2001.4551. PMID 11263980.
- ↑ "Entrez Gene: MFRP membrane frizzled-related protein".
Further reading
- Metlapally R, Li YJ, Tran-Viet KN, et al. (2008). "Common MFRP sequence variants are not associated with moderate to high hyperopia, isolated microphthalmia, and high myopia.". Mol. Vis. 14: 387–93. PMC 2268852. PMID 18334955.
- Ayala-Ramirez R, Graue-Wiechers F, Robredo V, et al. (2007). "A new autosomal recessive syndrome consisting of posterior microphthalmos, retinitis pigmentosa, foveoschisis, and optic disc drusen is caused by a MFRP gene mutation.". Mol. Vis. 12: 1483–9. PMID 17167404.
- Yang L, Yamasaki K, Shirakata Y, et al. (2006). "Bone morphogenetic protein-2 modulates Wnt and frizzled expression and enhances the canonical pathway of Wnt signaling in normal keratinocytes.". J. Dermatol. Sci. 42 (2): 111–9. doi:10.1016/j.jdermsci.2005.12.011. PMID 16442268.
- Pauer GJ, Xi Q, Zhang K, et al. (2006). "Mutation screen of the membrane-type frizzled-related protein (MFRP) gene in patients with inherited retinal degenerations.". Ophthalmic Genet. 26 (4): 157–61. doi:10.1080/13816810500374425. PMID 16352475.
- Mandal MN, Heckenlively JR, Burch T, et al. (2005). "Sequencing arrays for screening multiple genes associated with early-onset human retinal degenerations on a high-throughput platform.". Invest. Ophthalmol. Vis. Sci. 46 (9): 3355–62. doi:10.1167/iovs.05-0007. PMID 16123440.
- Sundin OH, Leppert GS, Silva ED, et al. (2005). "Extreme hyperopia is the result of null mutations in MFRP, which encodes a Frizzled-related protein.". Proc. Natl. Acad. Sci. U.S.A. 102 (27): 9553–8. doi:10.1073/pnas.0501451102. PMC 1172243. PMID 15976030.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Hayward C, Shu X, Cideciyan AV, et al. (2004). "Mutation in a short-chain collagen gene, CTRP5, results in extracellular deposit formation in late-onset retinal degeneration: a genetic model for age-related macular degeneration.". Hum. Mol. Genet. 12 (20): 2657–67. doi:10.1093/hmg/ddg289. PMID 12944416.
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