MCRS1

From Wikipedia, the free encyclopedia
Microspherule protein 1
Identifiers
SymbolsMCRS1; ICP22BP; INO80Q; MCRS2; MSP58; P78
External IDsOMIM: 609504 MGI: 1858420 HomoloGene: 4622 GeneCards: MCRS1 Gene
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez1044551812
EnsemblENSG00000187778ENSMUSG00000037570
UniProtQ96EZ8Q99L90
RefSeq (mRNA)NM_001012300NM_001164156
RefSeq (protein)NP_001012300NP_001157628
Location (UCSC)Chr 12:
49.95 – 49.96 Mb
Chr 15:
99.24 – 99.25 Mb
PubMed search

Microspherule protein 1 is a protein that in humans is encoded by the MCRS1 gene.[1][2][3]

Interactions

MCRS1 has been shown to interact with PHC2,[4] Death associated protein 6,[5] NOL1,[2] PINX1[6] and Telomerase reverse transcriptase.[6]

References

  1. Bruni R, Roizman B (Nov 1998). "Herpes simplex virus 1 regulatory protein ICP22 interacts with a new cell cycle-regulated factor and accumulates in a cell cycle-dependent fashion in infected cells". J Virol 72 (11): 8525–31. PMC 110262. PMID 9765390. 
  2. 2.0 2.1 Ren Y, Busch RK, Perlaky L, Busch H (Jul 1998). "The 58-kDa microspherule protein (MSP58), a nucleolar protein, interacts with nucleolar protein p120". Eur J Biochem 253 (3): 734–42. doi:10.1046/j.1432-1327.1998.2530734.x. PMID 9654073. 
  3. "Entrez Gene: MCRS1 microspherule protein 1". 
  4. Rual, Jean-François; Venkatesan Kavitha, Hao Tong, Hirozane-Kishikawa Tomoko, Dricot Amélie, Li Ning, Berriz Gabriel F, Gibbons Francis D, Dreze Matija, Ayivi-Guedehoussou Nono, Klitgord Niels, Simon Christophe, Boxem Mike, Milstein Stuart, Rosenberg Jennifer, Goldberg Debra S, Zhang Lan V, Wong Sharyl L, Franklin Giovanni, Li Siming, Albala Joanna S, Lim Janghoo, Fraughton Carlene, Llamosas Estelle, Cevik Sebiha, Bex Camille, Lamesch Philippe, Sikorski Robert S, Vandenhaute Jean, Zoghbi Huda Y, Smolyar Alex, Bosak Stephanie, Sequerra Reynaldo, Doucette-Stamm Lynn, Cusick Michael E, Hill David E, Roth Frederick P, Vidal Marc (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature (England) 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 
  5. Lin, Ding-Yen; Shih Hsiu-Ming (Jul 2002). "Essential role of the 58-kDa microspherule protein in the modulation of Daxx-dependent transcriptional repression as revealed by nucleolar sequestration". J. Biol. Chem. (United States) 277 (28): 25446–56. doi:10.1074/jbc.M200633200. ISSN 0021-9258. PMID 11948183. 
  6. 6.0 6.1 Song, Hai; Li Yiliang, Chen Guoyuan, Xing Zhen, Zhao Jing, Yokoyama Kazunari K, Li Tsaiping, Zhao Mujun (Apr 2004). "Human MCRS2, a cell-cycle-dependent protein, associates with LPTS/PinX1 and reduces the telomere length". Biochem. Biophys. Res. Commun. (United States) 316 (4): 1116–23. doi:10.1016/j.bbrc.2004.02.166. ISSN 0006-291X. PMID 15044100. 

Further reading


This article is issued from Wikipedia. The text is available under the Creative Commons Attribution/Share Alike; additional terms may apply for the media files.