LRP10

From Wikipedia, the free encyclopedia

Low density lipoprotein receptor-related protein 10

Identifiers

LRP10; LRP9; MST087

External IDs

OMIM: 609921 MGI: 1929480 HomoloGene: 8535 GeneCards: LRP10 Gene

Gene Ontology
Molecular function	• low-density lipoprotein receptor activity
Cellular component	• coated pit • integral to membrane
Biological process	• lipid metabolic process • lipid transport • inner ear development
Sources: Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

ENSG00000197324

ENSMUSG00000022175

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

Chr 14:
23.34 – 23.35 Mb

Chr 14:
54.46 – 54.47 Mb

PubMed search

Low-density lipoprotein receptor-related protein 10 is a protein that in humans is encoded by the LRP10 gene.^[1]^[2]

References

↑ Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA (Jun 1997). "Large-Scale Concatenation cDNA Sequencing". Genome Res 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
↑ "Entrez Gene: LRP10 low density lipoprotein receptor-related protein 10".

Further reading

Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
Sugiyama T, Kumagai H, Morikawa Y, et al. (2001). "A novel low-density lipoprotein receptor-related protein mediating cellular uptake of apolipoprotein E-enriched beta-VLDL in vitro". Biochemistry 39 (51): 15817–25. doi:10.1021/bi001583s. PMID 11123907.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Tomarev SI, Wistow G, Raymond V, et al. (2003). "Gene expression profile of the human trabecular meshwork: NEIBank sequence tag analysis". Invest. Ophthalmol. Vis. Sci. 44 (6): 2588–96. doi:10.1167/iovs.02-1099. PMID 12766061.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Wan D, Gong Y, Qin W, et al. (2004). "Large-scale cDNA transfection screening for genes related to cancer development and progression". Proc. Natl. Acad. Sci. U.S.A. 101 (44): 15724–9. doi:10.1073/pnas.0404089101. PMC 524842. PMID 15498874.

Lipids: lipoprotein particle metabolism

Lipoprotein particle classes and subclasses

delivery of TGs: Chylomicron
VLDL

delivery of C and CE: IDL
LDL
lb LDL
sd LDL
Lp(a)
HDL

Apolipoproteins

APOA
- 1
- 2
- 4
- 5
APOB
APOC
- 1
- 2
- 3
- 4
APOD
APOE
APOH

SAA
- SAA1

Extracellular enzymes

Lipid transfer proteins

Cell surface receptors

HDL: SCARB1

IDL: LRP
- LRP1
- LRP1B
- LRP2
- LRP3
- LRP4
- LRP5
- LRP5L
- LRP6
- LRP8
- LRP10
- LRP11
- LRP12

LDL: LDLR
LRPAP1

ATP-binding cassette transporter

M: MET

mt, k, c/g/r/p/y/i, f/h/s/l/o/e, a/u, n, m

k, cgrp/y/i, f/h/s/l/o/e, au, n, m, epon

m (A16/C10), i (k, c/g/r/p/y/i, f/h/s/o/e, a/u, n, m)

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