L-sorbose 1-dehydrogenase

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L-sorbose 1-dehydrogenase
Identifiers
EC number 1.1.99.32
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

L-sorbose 1-dehydrogenase (EC 1.1.99.32, SDH) is an enzyme with system name L-sorbose:acceptor 1-oxidoreductase.[1] This enzyme catalyses the following chemical reaction

L-sorbose + acceptor \rightleftharpoons 1-dehydro-L-sorbose + reduced acceptor

The product, L-sorbosone, is an intermediate in bacterial 2-keto-L-gulonic-acid formation. Co2+ stimulate activity of this membrane-bound enzyme, whili Cu2+ act as an inhibitor.

References

  1. Sugisawa, T., Hoshino, T., Nomura, S. and Fujiwara, A. (1991). "Isolation and characterization of membrane-bound L-sorbose dehydrogenase from Gluconobacter melanogenus UV10". Agric. Biol. Chem. 55: 363–370. 

External links

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