Keratoderma

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Keratoderma
Classification and external resources
ICD-10	L85.1, L86, Q82.8
ICD-9	701.1, 757.39

Keratoderma is a hornlike skin condition.^[1]

Classification

The keratodermas are classified into the following subgroups^[2]^:506:

Congenital

Simple keratodermas
- Diffuse palmoplantar keratodermas
  - Diffuse epidermolytic palmoplantar keratoderma
  - Diffuse nonepidermolytic palmoplantar keratoderma
  - mal de Meleda
- Focal palmoplantar keratoderma
  - Striate palmoplantar keratoderma
- Punctate palmoplantar keratoderma
  - Keratosis punctata palmaris et plantaris
  - Spiny keratoderma
  - Focal acral hyperkeratosis
Complex keratodermas
- Diffuse palmoplantar keratoderma
  - Erythrokeratodermia variabilis
  - Palmoplantar keratoderma of Sybert
  - Olmsted syndrome
  - Naegeli-Franceschetti-Jadassohn syndrome
- Focal palmoplantar keratoderma
  - Papillon-Lefèvre syndrome
  - Pachyonychia congenita type I
  - Pachyonychia congenita type II
  - Focal palmoplantar keratoderma with oral mucosal hyperkeratosis
  - Camisa disease
- Ectodermal dysplasias
  - Clouston's hidrotic ectodermal dysplasia
  - Acrokeratotic poikiloderma
  - Dermatopathic pigmentosa reticularis
- Syndromic keratodermas
  - Vohwinkel syndrome
  - Palmoplantar keratoderma associated with esophageal cancer
  - Palmoplantar keratoderma and spastic paraplegia
  - Naxos disease
  - Striate palmoplantar keratoderma, woolly hair, and left ventricular dilated cardiomyopathy
  - Keratitis-ichthyosis-deafness syndrome
  - Corneodermatosseous syndrome
  - Huriez syndrome
  - Oculocutaneous tyrosinemia
  - Cardiofaciocutaneous syndrome
  - Schöpf-Schulz-Passarge syndrome

Acquired

Acquired keratodermas
- AIDS-associated keratoderma
- Arsenical keratoses
- Calluses
- Climacteric keratoderma
- Clavi (Corns)
- Eczema
- Human papillomavirus
- Keratoderma blenorrhagicum
- Lichen planus
- Norwegian scabies
- Paraneoplastic keratoderma
- Psoriasis
- Reiter's syndrome
- Secondary syphilis
- Tinea pedis
- Sézary syndrome
- Tuberculosis verrucosa cutis
- Drug-induced keratoderma^[3]

References

↑ WordNet Search - 3.0
↑ Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0-07-138076-0.
↑ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. p. 778. ISBN 1-4160-2999-0.

Cutaneous keratosis, ulcer, atrophy, and necrobiosis (L82–L94, 700–701.5)

Epidermal thickening

keratoderma: Keratoderma climactericum
Paraneoplastic keratoderma
- Acrokeratosis paraneoplastica of Bazex
Aquagenic keratoderma
Drug-induced keratoderma
Paraneoplastic keratoderma
psoriasis
- Keratoderma blennorrhagicum

other hyperkeratosis: Acanthosis nigricans
- Confluent and reticulated papillomatosis
Callus
Ichthyosis acquisita
Arsenical keratosis
Chronic scar keratosis
Hyperkeratosis lenticularis perstans
Hydrocarbon keratosis
Hyperkeratosis of the nipple and areola
Inverted follicular keratosis
Lichenoid keratosis
Multiple minute digitate hyperkeratosis
PUVA keratosis
Reactional keratosis
Stucco keratosis
Thermal keratosis
Viral keratosis
Warty dyskeratoma
Waxy keratosis of childhood

Necrobiosis/granuloma

Necrobiotic/palisading	Granuloma annulare Perforating Generalized Subcutaneous Granuloma annulare in HIV disease Localized granuloma annulare Patch-type granuloma annulare Necrobiosis lipoidica Annular elastolytic giant cell granuloma Granuloma multiforme Necrobiotic xanthogranuloma Palisaded neutrophilic and granulomatous dermatitis Rheumatoid nodulosis Interstitial granulomatous dermatitis/Interstitial granulomatous drug reaction

Foreign body granuloma	Beryllium granuloma Mercury granuloma Silica granuloma Silicone granuloma Zirconium granuloma Soot tattoo Tattoo Carbon stain

Other/ungrouped	eosinophilic dermatosis Granuloma faciale

Dermis/
localized CTD

Cutaneous lupus erythematosus	chronic: Discoid Panniculitis subacute: Neonatal ungrouped: Chilblain Lupus erythematosus–lichen planus overlap syndrome Tumid Verrucous Rowell's syndrome

Scleroderma/ Morphea	Localized scleroderma Localized morphea Morphea–lichen sclerosus et atrophicus overlap Generalized morphea Atrophoderma of Pasini and Pierini Pansclerotic morphea Morphea profunda Linear scleroderma

Atrophic/ atrophoderma	Lichen sclerosus Anetoderma Schweninger–Buzzi anetoderma Jadassohn–Pellizzari anetoderma Atrophoderma of Pasini and Pierini Acrodermatitis chronica atrophicans Semicircular lipoatrophy Follicular atrophoderma Linear atrophoderma of Moulin

Perforating	Kyrle disease Reactive perforating collagenosis Elastosis perforans serpiginosa Perforating folliculitis Acquired perforating dermatosis

Skin ulcer	Pyoderma gangrenosum

Other	Calcinosis cutis Sclerodactyly Poikiloderma vasculare atrophicans Ainhum/Pseudo-ainhum

M: INT, SF, LCT

anat/phys/devp

noco (i/b/d/q/u/r/p/m/k/v/f)/cong/tumr (n/e/d), sysi/epon

proc, drug (D2/3/4/5/8/11)

Congenital malformations and deformations of integument / skin disease (Q80–Q82, 757.0–757.3)

Genodermatosis

Congenital ichthyosis/
erythrokeratodermia

AD	Ichthyosis vulgaris

AR	Congenital ichthyosiform erythroderma: Epidermolytic hyperkeratosis Lamellar ichthyosis Harlequin type ichthyosis Netherton syndrome Zunich–Kaye syndrome Sjögren–Larsson syndrome

XR	X-linked ichthyosis

Ungrouped	Ichthyosis bullosa of Siemens Ichthyosis follicularis Ichthyosis prematurity syndrome Ichthyosis–sclerosing cholangitis syndrome Nonbullous congenital ichthyosiform erythroderma Ichthyosis linearis circumflexa Ichthyosis hystrix

EB
and related

EBS
- EBS-K
- EBS-WC
- EBS-DM
- EBS-OG
- EBS-MD
- EBS-MP

JEB
- JEB-H
- Mitis
- Generalized atrophic
- JEB-PA

DEB
- DDEB
- RDEB

Ectodermal dysplasia

Elastic/Connective

Ehlers–Danlos syndrome
Cutis laxa (Gerodermia osteodysplastica)
Popliteal pterygium syndrome
Pseudoxanthoma elasticum
Van Der Woude syndrome

Hyperkeratosis/
keratinopathy

PPK	diffuse: Diffuse epidermolytic palmoplantar keratoderma Diffuse nonepidermolytic palmoplantar keratoderma Palmoplantar keratoderma of Sybert Mal de Meleda syndromic connexin Bart–Pumphrey syndrome Clouston's hidrotic ectodermal dysplasia Vohwinkel syndrome Corneodermatoosseous syndrome plakoglobin Naxos syndrome Scleroatrophic syndrome of Huriez Olmsted syndrome Cathepsin C Papillon–Lefèvre syndrome Haim–Munk syndrome Camisa disease focal: Focal palmoplantar keratoderma with oral mucosal hyperkeratosis Focal palmoplantar and gingival keratosis Howel–Evans syndrome Pachyonychia congenita Pachyonychia congenita type I Pachyonychia congenita type II Striate palmoplantar keratoderma Tyrosinemia type II punctate: Acrokeratoelastoidosis of Costa Focal acral hyperkeratosis Keratosis punctata palmaris et plantaris Keratosis punctata of the palmar creases Schöpf–Schulz–Passarge syndrome Porokeratosis plantaris discreta Spiny keratoderma ungrouped: Palmoplantar keratoderma and spastic paraplegia desmoplakin Carvajal syndrome connexin Erythrokeratodermia variabilis HID/KID

Other	Meleda disease Keratosis pilaris ATP2A2 Darier's disease Dyskeratosis congenita Lelis syndrome Dyskeratosis congenita Keratolytic winter erythema Keratosis follicularis spinulosa decalvans Keratosis linearis with ichthyosis congenital and sclerosing keratoderma syndrome Keratosis pilaris atrophicans faciei Keratosis pilaris

Other

see also Template:Congenital malformations and deformations of skin appendages, Template:Phakomatoses, Template:Pigmentation disorders, Template:DNA replication and repair-deficiency disorder

Developmental
anomalies

Midline	Dermoid cyst Encephalocele Nasal glioma PHACE association Sinus pericranii

Nevus	Capillary hemangioma Port-wine stain Nevus flammeus nuchae

Other/ungrouped	Aplasia cutis congenita Amniotic band syndrome Branchial cyst Cavernous venous malformation Accessory nail of the fifth toe Bronchogenic cyst Congenital cartilaginous rest of the neck Congenital hypertrophy of the lateral fold of the hallux Congenital lip pit Congenital malformations of the dermatoglyphs Congenital preauricular fistula Congenital smooth muscle hamartoma Cystic lymphatic malformation Median raphe cyst Melanotic neuroectodermal tumor of infancy Mongolian spot Nasolacrimal duct cyst Omphalomesenteric duct cyst Poland anomaly Rapidly involuting congenital hemangioma Rosenthal–Kloepfer syndrome Skin dimple Superficial lymphatic malformation Thyroglossal duct cyst Verrucous vascular malformation Birthmark