Johann Jakob Wepfer

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Johann Jakob Wepfer (December 23, 1620 – January 26, 1695) was a Swiss pathologist and pharmacologist who was a native of Schaffhausen.

He studied medicine in Strasbourg, Basel and Padua, and in 1647 returned to Schaffhausen to practice medicine. Here he maintained a practice that extended into southern Germany. During his career he also served as a private physician and consultant to various members of royalty.

Wepfer is remembered for his work involving vascular anatomy of the brain, and the study of cerebrovascular disease. He was the first physician to hypothesize that the effects of a stroke were caused by bleeding in the brain. He also mentioned that these symptoms could be caused by a blockage of one of the main arteries that supply blood to the brain. From postmortem studies, he provided information on the carotid and vertebral arteries that supply the brain with blood. in 1658 he published a classic treatise on strokes, titled Historiae apoplecticorum.

Wepfer made important contributions in the fields of experimental pharmacology and toxicology. He conducted experiments on the toxicity of water hemlock, hellebore, monkshood,^[1] and warned against the usage of arsenic, antimony, and mercury in medicine. In the fields of pharmacology/toxicology he published an influential work on water and poison hemlock called Cicutae aquaticae historia et noxae (1679).^[2]

Since 2005 an annual award for stroke research, named after Wepfer, is awarded at the European stroke conference.,^[3]^[4]

References

Brain Embolism by Louis R. Caplan, Warren J. Manning
Johann Wepfer and Vascular Anatomy of the Brain
Galileo Project (biography of Johann Jacob Wepfer)

↑ Essays in the history of therapeutics by William F. Bynum, et al
↑ viaLibri Resources for Bibliophiles
↑ "The "Johann Jacob Wepfer Award"". Retrieved 2009-07-21.
↑ Bousser, M. G. (2008). "Some translations in vascular neurology. The Johann Jacob Wepfer Award 2008". Cerebrovascular diseases (Basel, Switzerland) 26 (3): 328–334. doi:10.1159/000151589. ISSN 1015-9770. PMID 18724046.

Authority control	WorldCat VIAF: 37712076 LCCN: n83007778 ISNI: 0000 0001 0888 9973 GND: 118767003 HDS: 14690

Persondata
Name	Wepfer, Johann Jakob
Alternative names
Short description	Swiss pathologist
Date of birth	December 23, 1620
Place of birth
Date of death	January 26, 1695
Place of death

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