Isovaleramide

Isovaleramide
IUPAC name 3-Methylbutanamide
Other names Isopentanamide Isovaleric acid amide Isovaleric amide beta-Methylbutyramide
Identifiers
CAS number	541-46-8 Y
PubChem	10930
	UNII	9CP4KB634M Y
KEGG	D04637 Y
Jmol-3D images	Image 1
SMILES CC(C)CC(=O)N
Properties
Molecular formula	C5H11NO
Molar mass	101.15 g mol−1
Appearance	colourless solid
Melting point	137 °C; 279 °F; 410 K
Boiling point	226 °C; 439 °F; 499 K
Y (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Isovaleramide is an organic compound with the formula (CH₃)₂CHCH₂C(O)NH₂. The amide derived from isovaleric acid, it is a colourless solid.

Occurrence and biological activity

Isovaleramide is found in the Valerian root.

In humans, it acts as a mild anxiolytic at lower doses and as a mild sedative at higher dosages.^[1] Isovaleramide has been shown to be non-cytotoxic and does not act as a CNS stimulant. It inhibits the liver alcohol dehydrogenases and has a reported LD₅₀ of greater than 400 mg/kg when administered intraperitoneally in mice.^[2]

References