Indecainide

From Wikipedia, the free encyclopedia

Indecainide

Systematic (IUPAC) name
9-[3-(isopropylamino)propyl]-9H-fluorene-9-carboxamide
Clinical data
Legal status	?
Identifiers
CAS number	74517-78-5^Y 73681-12-6 (HCl)
ATC code	None
PubChem	CID 52194
DrugBank	DB00192
ChemSpider	47194^Y
UNII	3AZF20DM1T^Y
KEGG	D04521^Y
ChEMBL	CHEMBL1201242^N
Chemical data
Formula	C₂₀H₂₄N₂O
Mol. mass	308.42 g/mol
SMILES O=C(N)C3(c1ccccc1c2c3cccc2)CCCNC(C)C
InChI InChI=1S/C20H24N2O/c1-14(2)22-13-7-12-20(19(21)23)17-10-5-3-8-15(17)16-9-4-6-11-18(16)20/h3-6,8-11,14,22H,7,12-13H2,1-2H3,(H2,21,23)^Y Key:UCEWGESNIULAGX-UHFFFAOYSA-N^Y
N (what is this?) (verify)

Indecainide (INN, trade name Decabid) is a class Ic antiarrhythmic agent. Developed and marketed by Lilly, it has now been discontinued.

External links

FDA drug details

class Ia (Phase 0→ and Phase 3→)	Ajmaline Disopyramide Lorajmine Prajmaline Procainamide^# Quinidine^# Sparteine

class Ib (Phase 3←)	IV (Lidocaine^#) enteral (Aprindine Mexiletine Tocainide)

class Ic (Phase 0→)	Encainide^‡ Ethacizine Flecainide Indecainide^‡ Lorcainide Moracizine^‡ Propafenone

class III
(Phase 3→, K⁺ channel blockers)

class IV
(Phase 4→, Ca²⁺ channel blockers)

class II (Phase 4→, β blockers)	Nadolol Pindolol Propranolol cardioselective (Acebutolol Atenolol Esmolol Metoprolol)

A₁ agonist	Adenosine Benzodiazepines Barbiturates

M₂	muscarinic antagonist: Atropine Disopyramide Quinidine muscarinic agonist: Digoxin

α receptors	Amiodarone Bretylium Quinidine Verapamil

Na⁺ / K⁺-ATPase	Digoxin

anat/phys/devp

noco/cong/tumr, sysi/epon, injr

proc, drug (C1A/1B/1C/1D), blte

This article is issued from Wikipedia. The text is available under the Creative Commons Attribution/Share Alike; additional terms may apply for the media files.