Honeycombing

Honeycombing is a lung condition defined by the presence of small cystic spaces with irregularly thickened walls composed of fibrous tissue. Honeycomb cysts often predominate in the peripheral and subpleural lung regions regardless of their cause.

Subpleural honeycomb cysts typically occur in several contiguous layers. This finding can allow honeycombing to be distinguished from paraseptal emphysema in which subpleural cysts usually occur in a single layer.