Harminder Dua
Harminder Singh Dua (born in Jalandhar, Punjab) is an Indian-British medical doctor and researcher (with MBBS, DO, DO (Lond), MS, MNAMS, FRCS, FRCOphth., FEBO, MD, PhD).[1] He is the chair and professor of ophthalmology at University of Nottingham and is the head of the Division of Ophthalmology and Visual Sciences. Prior, he was associate professor at the Thomas Jefferson University, Philadelphia, USA when he was invited to chair in Nottingham in April 1994.He earlier did his Graduation in Medicine from Government Medical College and Hospital,Nagpur.[2]
Dua is also the co-editor in chief with Arun Singh, of the British Journal of Ophthalmology. He is president of EuCornea, the European society of Cornea and Ocular surface disease specialists. He is also president of the EVERf (European Association for Vision and Eye Research Foundation) and past president of the association itself. He was elected to the chair of Academia Ophthalmologica Internationalis and invited to join as member of the American Ophthalmological Society by thesis. In March 2011 he was elected president of the Royal College of Ophthalmologists, UK commencing his duties on 25 May 2011. He has over 200 research publications, 20 published letters, and 14 book chapters to his credit.[1]
Discovery of Dua's layer
In a 2013 paper, Dua and others at the University of Nottingham[3] reported discovery of a previously unknown layer of the human cornea measuring just 15 micrometres thick between the corneal stroma and Descemet's membrane.[4] They refer to the reported layer as Dua's layer.
Bibliography
Harminder S Dua has over 270 scientific publications. The latest 50 are given below:
1. Otri AM, Mohammed I, Abedin A, Cao Z, Hopkinson A, Panjwani N, Dua HS. Antimicrobial peptides expression by ocular surface cells in response to Acanthamoeba castellanii: an in vitro study. Br J Ophthalmol. 2010 Nov;94(11):1523-7. Epub 2010 Aug 1
2. Dua HS, Rahman I, Miri A, Said DG. Variations in amniotic membrane: relevance for clinical applications. Br J Ophthalmol. 2010 Aug;94(8):963-4.
3. Fares U, Mushtaq F, Said D, Dua HS. Keratopathy: white patches, clear dots and grey lines. Br J Ophthalmol. 2010 Sep 9. [Epub ahead of print]
4. Mohammed I, Yeung A, Abedin A, Hopkinson A, Dua HS. Signalling pathways involved in ribonuclease-7 expression. Cell Mol Life Sci. 2011; 68:1941-52. doi: 10.1007/s00018-010-0540-2. Epub 2010 Oct 22
5. Kulkarni BB, Tighe PJ, Mohammed I, Yeung AM, Powe DG, Hopkinson A, Shanmuganathan VA, Dua HS. Comparative transcriptional profiling of the limbal epithelial crypt demonstrates its putative stem cell niche characteristics. BMC Genomics. 2010 Sep 29;11:526. http://www.biomedcentral.com/1471-2164/11/526
6. Alomar TS, Nubile M, Lowe J, Dua HS. Corneal intraepithelial neoplasia: in vivo confocal microscopic study with histopathologic correlation. Am J Ophthalmol. 2011 Feb;151(2):238-47. Epub 2010 Dec 18.
7. Nubile M, Dua HS, Lanzini M, Ciancaglini M, Calienno R, Said DG, Pocobelli A, Mastropasqua R, Carpineto P. In vivo analysis of stromal integration of multilayer amniotic membrane transplantation in corneal ulcers. Am J Ophthalmol. 2011 May;151(5):809-822.e1. Epub 2011 Feb 18.
8. Al-Aqaba M, Alomar T, Lowe J, Dua HS. Corneal nerve aberrations in bullous keratopathy. Am J Ophthalmol. 2011 May;151(5):840-849.e1. Epub 2011 Feb 18.
9. Miri A, Said DG, Dua HS. Donor Site Complications in Autolimbal and Living-Related Allolimbal Transplantation. Ophthalmology. 2011 Mar 30. [Epub ahead of print]
10. Dua HS, Said DG. Much froth over bubbles. Br J Ophthalmol. 2011 Apr 15.
11. Mohammed I, Abedin A, Tsintzas K, Abedin SA, Otri AM, Hopkinson A, Mathew M, Dua HS. Increased expression of hepcidin and toll-like receptors 8 and 10 in viral keratitis. Cornea. 2011 Aug;30(8):899-904.
12. Al-Aqaba MA, Faraj L, Fares U, Otri AM, Dua HS. The morphologic characteristics of corneal nerves in advanced keratoconus as evaluated by acetylcholinesterase technique. Am J Ophthalmol. 2011 Sep;152(3):364-376.e1. Epub 2011 Jun 16.
13. Cursiefen C, Colin J, Dana R, Diaz-Llopis M, Faraj LA, Garcia-Delpech S, Geerling G, Price FW, Remeijer L, Rouse BT, Seitz B, Udaondo P, Meller D, Dua H. Consensus statement on indications for anti-angiogenic therapy in the management of corneal diseases associated with neovascularisation: outcome of an expert roundtable Br J Ophthalmol. 2012; 96:3-9. doi: 10.1136/bjo.2011.204701. Epub 2011 Jun 28
14. Fares U, Suleman H, Al-Aqaba MA, Otri AM, Said DG, Dua HS. Efficacy, predictability, and safety of wavefront-guided refractive laser treatment: Metaanalysis. J Cataract Refract Surg. 2011 Aug;37(8):1465-75.
15. Kulkarni B, Mohammed I, Hopkinson A, Dua HS. Validation of endogenous control genes for gene expression studies on human ocular surface epithelium. PLoS One. 2011;6(8):e22301. Epub 2011 Aug 3
16. Fares U, Otri AM, Al-Aqaba MA, Dua HS. Correlation of central and peripheral corneal thickness in healthy corneas. Cont Lens Anterior Eye. 2011 Aug 30. [Epub ahead of print]
17. Alomar TS, Al-Aqaba M, Gray T, Lowe J, Dua HS. Histological and Confocal Microscopy Changes in Chronic Corneal Edema: Implications for Endothelial Transplantation. Invest Ophthalmol Vis Sci. 2011 Sep 6. [Epub ahead of print]
18. Al-Aqaba MA, Otri AM, Fares U, Miri A, Dua HS. Organization of the Regenerated Nerves in Human Corneal Grafts. Am J Ophthalmol. 2011 Sep 8. [Epub ahead of print]
19. Al-Aqaba M, Calienno R, Fares U, Otri AM, Mastropasqua L, Nubile M, Dua HS. The Effect of Standard and Transepithelial Ultraviolet Collagen Cross-Linking on Human Corneal Nerves: An Ex Vivo Study. Am J Ophthalmol. 2011 Sep 17. [Epub ahead of print]
20. Faraj LA, Said DG, Dua HS. Evaluation of corneal neovascularisation. Br J Ophthalmol. 2011 Oct;95(10):1343-4.
21. Faraj LA, Hashmani K, Dua HS. The power of a bubble: Descemet's stripping endothelial keratoplasty (DSEK) and rebubbling. Br J Ophthalmol. 2011 Nov;95(11):1481-2.
22. Said DG, Otri M, Miri A, Kailasanathan A, Khatib T, Dua HS. The challenge of fungal keratitis. Br J Ophthalmol. 2011 Dec;95(12):1623-4
23. Otri AM, Fares U, Al-Aqaba MA, Dua HS. Corneal densitometry as an indicator of corneal health.Ophthalmology. 2012 Mar;119(3):501-8. Epub 2011 Nov 30.
24. Bhatt UK, Fares U, Rahman I, Said DG, Maharajan SV, Dua HS. Outcomes of deep anterior lamellar keratoplasty following successful and failed 'big bubble'. Br J Ophthalmol. 2012 Apr;96(4):564-9. Epub 2011 Dec 1.
25. Otri AM, Mohammed I, Al-Aqaba MA, Fares U, Peng C, Hopkinson A, Dua HS. Variable expression of human Beta defensins 3 and 9 at the human ocular surface in infectious keratitis. Invest Ophthalmol Vis Sci. 2012 Feb 16;53(2):757-61. Print 2012 Feb.
26. Miri A, Alomar T, Nubile M, Al-Aqaba M, Lanzini M, Fares U, Said DG, Lowe J, Dua HS. In vivo confocal microscopic findings in patients with limbal stem cell deficiency. Br J Ophthalmol. 2012 Apr;96(4):523-9. Epub 2012 Feb 10.
27. Miri A, Al-Aqaba M, Otri AM, Fares U, Said DG, Faraj LA, Dua HS. In vivo confocal microscopic features of normal limbus. Br J Ophthalmol. 2012 Apr;96(4):530-6. Epub 2012 Feb 10.
28. Faraj LA, Hashmani K, Khatib T, Al-Aqaba M, Dua HS. The changing face of corneal graft rejection. Br J Ophthalmol. 2012 Apr 29. [Epub ahead of print].
29. Miri A, Hashmani K, Al-Aqaba M, Faraj LA, Fares U, Otri AM, Said DG, Dua HS. The effect of gravitational force on limbal stem cell growth. Br J Ophthalmol. 2012; 96(7):1034-7. doi: 10.1136/bjophthalmol-2012-301624. Epub 2012 May 19.
30. Branch MJ, Hashmani K, Dhillon P, Jones DR, Dua HS, Hopkinson A. Mesenchymal stem cells in the human corneal limbal stroma. Invest Ophthalmol Vis Sci. 2012; 53:5109-16. doi: 10.1167/iovs.11-8673.
31. Chau DY, Brown SV, Mather ML, Hutter V, Tint NL, Dua HS, Rose FR, Ghaemmaghami AM. Tissue transglutaminase (TG-2) modified amniotic membrane: a novel scaffold for biomedical applications. Biomed Mater. 2012 Jun 1;7(4):045011. [Epub ahead of print]
32. Otri AM, Fares U, Al-Aqaba MA, Miri A, Faraj LA, Said DG, Maharajan S, Dua HS. Profile of sight-threatening infectious keratitis: a prospective study. Acta Ophthalmol. 2012 Aug 3. doi: 10.1111/j.1755-3768.2012.02489.x. [Epub ahead of print
33. Clare G, Suleman H, Bunce C, Dua H. Amniotic membrane transplantation for acute ocular burns. Cochrane Database Syst Rev. 2012 Sep 12;9:CD009379. doi: 10.1002/14651858.CD009379.pub2
34. Bhatt UK, Faraj LA, Dhillon V, Dua HS. Visual outcomes in corneal transplantation. Br J Ophthalmol. 2012 Sep 18. [Epub ahead of print]
35. Fares U, Sarhan AR, Dua HS. Management of post-keratoplasty astigmatism. J Cataract Refract Surg. 2012 Nov;38(11):2029-39. doi: 10.1016/j.jcrs.2012.09.002.
36. Fares U, Otri AM, Al-Aqaba MA, Faraj L, Dua HS. Wavefront-optimized excimer laser in situ keratomileusis for myopia and myopic astigmatism: Refractive outcomes and corneal densitometry. J Cataract Refract Surg. 2012 Oct 17. doi:pii: S0886-3350(12)01331-4. 10.1016/j.jcrs.2012.07.041. [Epub ahead of print]
37. Bhatt UK, Sheppard AL, Shah S, Dua HS, Mihashi T, Yamaguchi T, Wolffsohn JS. Design and validity of a miniaturized open-field aberrometer. J Cataract Refract Surg. 2012 Oct 27. doi:pii: S0886-3350(12)01305-3. 10.1016/j.jcrs.2012.08.052. [Epub ahead of print]
38. Perrella G, Scott CA, Spelat R, Brusini P, D’Aurizio F, De Pol I, and Dua HS. Cultured Human Keratocytes from the Limbus and Cornea Both Express Epithelial Cytokeratin 3: Possible Mesenchymal-Epithelial Transition. Int J Ophthalmic Pathol 2012; 1:2.
39. Nubile M, Curcio C, Dua HS, Calienno R, Lanzini M, Iezzi M, Mastropasqua R, Agnifili L, Mastropasqua L. Pathological changes of the anatomical structure and markers of the limbal stem cell niche due to inflammation. Mol Vis. 2013;19:516-25. Epub 2013 Feb 26.
40. Gandhewar J, Savant V, Prydal J, Dua H. Double Drape Tectonic Patch With Cyanoacrylate Glue in the Management of Corneal Perforation With Iris Incarceration. Cornea. 2013 May;32(5):e137-8. doi: 10.1097/ICO.0b013e3182801809
41. Fares U, Mokashi AA, Al-Aqaba MA, Otri AM, Miri A, Dua HS. Management of postkeratoplasty astigmatism by paired arcuate incisions with compression sutures. Br J Ophthalmol. 2013 Apr;97(4):438-43. doi: 10.1136/bjophthalmol-2012-302128. Epub 2013 Feb 6.
42. Alomar TS, Mahmood K, O'Connor S, Robson K, Dua HS. Localized conjunctival extra-nodal marginal zone B cell lymphoma with presumed paraproteinic crystalline keratopathy. Int Ophthalmol. 2013 Jan 30. [Epub ahead of print]
43. Nubile M, Lanzini M, Miri A, Pocobelli A, Calienno R, Curcio C, Mastropasqua R, Dua HS, Mastropasqua L. In vivo confocal microscopy in diagnosis of limbal stem cell deficiency. Am J Ophthalmol. 2013 Feb;155(2):220-32. doi: 10.1016/j.ajo.2012.08.017. Epub 2012 Nov 3.
44. Forrester JV, Steptoe RJ, Klaska IP, Martin-Granados C, Dua HS, Degli-Esposti MA, Wikstrom ME. CelI-based therapies for ocular inflammation. Prog Retin Eye Res. 2013 Mar 29. doi:pii: S1350-9462(13)00016-5. 10.1016/j.preteyeres.2013.02.002. [Epub ahead of print]
45. Baxter JM, Lee R, Sharp JA, Foss AJ; Intensive Cataract Training Study Group, Vernon SA, Maharajan S, Kumudhan D, Thomas S, Dhar-Munshi S, Subramaniam S, Scheepers M, Lakshmanan A, Maharajan P, Steel T, Alexander P, Tint N, Tildsley J, Williams D, Abercrombie L, Amoaku W, Dua H, Gregson R, King A, Lim C, Munshi V, Nithianandan P, Orr G, Tambe K, Zaman A. Intensive cataract training: a novel approach. Eye (Lond). 2013 Apr 19. doi: 10.1038/eye.2013.54. [Epub ahead of print]
46. Dua HS, Faraj LA, Said DG, Gray T, Lowe J. Human Corneal Anatomy Redefined: A Novel Pre-Descemet’s Layer (Dua’s Layer). Ophthalmology 2013 May 25. Pii:S0161-6420(13)00020-1. Doi:10.1016/jophtha.2013.01.018. (Epub ahead of print).
47. Paris FD, Goncalves ED, Campos MS, Sato EH, Dua HS, Gomes JA. (Joint senior author). Amniotic membrane transplantation versus Anterior stromal puncture in bullous keratopathy: a comparative study. Br J Ophthalmol. 2013 May 30, (Epub ahead of print).
48. Fares U, Mokashi AA, Elalfy MA, Dua HS. Sequential selective same-day suture removal in the management of post-keratoplasty astigmatism. Eye 2013 July 7. doi: 10.1038/eye.2013.126. (Epub ahead of print).
49. Hashmani K, Branch MJ, Sidney LE, Dhillon PS, Verma M, McIntosh OD, Hopkinson A, Dua HS. Characterization of corneal stromal stem cells with the potential for epithelial transdifferentiation. Stem Cell Res Ther. 2013; 4:75. [Epub ahead of print]
50. Allen CL, Clare G, Stewart EA, Branch MJ, McIntosh OD, Dadhwal M, Dua HS, Hopkinson A. Augmented Dried versus Cryopreserved Amniotic Membrane as an Ocular Surface Dressing. PLoS One. 2013 Oct 30;8(10):e78441. doi: 10.1371/journal.pone.0078441.
References
- ↑ 1.0 1.1 BMJ: Harminder Singh Dua biography
- ↑ http://www.telegraphindia.com/1130613/jsp/nation/story_17002533.jsp#.UnAFR_nryc8
- ↑ Kristin Butler (June 12, 2013). "Scientists discover new layer of human cornea". UPI. Retrieved June 12, 2013.
- ↑ Dua, H. S.; Faraj, L. A.; Said, D. G.; Gray, T.; Lowe, J. (2013). "Human Corneal Anatomy Redefined: A Novel Pre-Descemet's Layer (Dua's Layer)". Ophthalmology 120 (9): 1778–1785. doi:10.1016/j.ophtha.2013.01.018. PMID 23714320.