HSPA6
From Wikipedia, the free encyclopedia
| Heat shock 70kDa protein 6 (HSP70B') | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 PDB rendering based on 1xqs. | |||||||||||||
| |||||||||||||
| Identifiers | |||||||||||||
| Symbol | HSPA6 | ||||||||||||
| External IDs | OMIM: 140555 HomoloGene: 105648 GeneCards: HSPA6 Gene | ||||||||||||
| |||||||||||||
| RNA expression pattern | |||||||||||||
 | |||||||||||||
 | |||||||||||||
| More reference expression data | |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 3310 | n/a | |||||||||||
| Ensembl | ENSG00000173110 | n/a | |||||||||||
| UniProt | P17066 | n/a | |||||||||||
| RefSeq (mRNA) | NM_002155 | n/a | |||||||||||
| RefSeq (protein) | NP_002146 | n/a | |||||||||||
| Location (UCSC) | Chr 1: 161.49 – 161.5 Mb | n/a | |||||||||||
| PubMed search | n/a | ||||||||||||
Heat shock 70 kDa protein 6 is a protein that in humans is encoded by the HSPA6 gene.[1][2]
References
- ↑ Leung TK, Hall C, Rajendran M, Spurr NK, Lim L (Mar 1992). "The human heat-shock genes HSPA6 and HSPA7 are both expressed and localize to chromosome 1". Genomics 12 (1): 74–9. doi:10.1016/0888-7543(92)90409-L. PMID 1346391.
- ↑ "Entrez Gene: HSPA6 heat shock 70kDa protein 6 (HSP70B')".
Further reading
- Leung TK, Rajendran MY, Monfries C, et al. (1990). "The human heat-shock protein family. Expression of a novel heat-inducible HSP70 (HSP70B') and isolation of its cDNA and genomic DNA.". Biochem. J. 267 (1): 125–32. PMC 1131254. PMID 2327978.
- Schiller P, Amin J, Ananthan J, et al. (1988). "Cis-acting elements involved in the regulated expression of a human HSP70 gene.". J. Mol. Biol. 203 (1): 97–105. doi:10.1016/0022-2836(88)90094-0. PMID 3184191.
- Rensing SA, Maier UG (1994). "Phylogenetic analysis of the stress-70 protein family.". J. Mol. Evol. 39 (1): 80–6. doi:10.1007/BF00178252. PMID 7545947.
- Furlini G, Vignoli M, Re MC, et al. (1994). "Human immunodeficiency virus type 1 interaction with the membrane of CD4+ cells induces the synthesis and nuclear translocation of 70K heat shock protein.". J. Gen. Virol. 75 (1): 193–9. doi:10.1099/0022-1317-75-1-193. PMID 7906708.
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- Mercier PA, Winegarden NA, Westwood JT (1999). "Human heat shock factor 1 is predominantly a nuclear protein before and after heat stress.". J. Cell. Sci. 112. ( Pt 16): 2765–74. PMID 10413683.
- O'Keeffe B, Fong Y, Chen D, et al. (2000). "Requirement for a kinase-specific chaperone pathway in the production of a Cdk9/cyclin T1 heterodimer responsible for P-TEFb-mediated tat stimulation of HIV-1 transcription.". J. Biol. Chem. 275 (1): 279–87. doi:10.1074/jbc.275.1.279. PMID 10617616.
- Agostini I, Popov S, Li J, et al. (2000). "Heat-shock protein 70 can replace viral protein R of HIV-1 during nuclear import of the viral preintegration complex.". Exp. Cell Res. 259 (2): 398–403. doi:10.1006/excr.2000.4992. PMID 10964507.
- Gurer C, Cimarelli A, Luban J (2002). "Specific incorporation of heat shock protein 70 family members into primate lentiviral virions.". J. Virol. 76 (9): 4666–70. doi:10.1128/JVI.76.9.4666-4670.2002. PMC 155079. PMID 11932435.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Lim MC, Brooke SM, Sapolsky RM (2003). "gp120 neurotoxicity fails to induce heat shock defenses, while the over expression of hsp70 protects against gp120.". Brain Res. Bull. 61 (2): 183–8. doi:10.1016/S0361-9230(03)00113-8. PMID 12832005.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
| ||||||||
External links
- HSPA6 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
| ||||||||||||||||||||||
This article is issued from Wikipedia. The text is available under the Creative Commons Attribution/Share Alike; additional terms may apply for the media files.