HEXIM2
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| Hexamethylene bis-acetamide inducible 2 | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | HEXIM2; FLJ32384; L3 | ||||||||||||
| External IDs | MGI: 1918309 HomoloGene: 16946 GeneCards: HEXIM2 Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
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| More reference expression data | |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 124790 | 71059 | |||||||||||
| Ensembl | ENSG00000168517 | ENSMUSG00000043372 | |||||||||||
| UniProt | Q96MH2 | Q3TVI4 | |||||||||||
| RefSeq (mRNA) | NM_144608 | NM_001130515 | |||||||||||
| RefSeq (protein) | NP_653209 | NP_001123987 | |||||||||||
| Location (UCSC) | Chr 17: 43.24 – 43.25 Mb | Chr 11: 103.13 – 103.14 Mb | |||||||||||
| PubMed search | |||||||||||||
Protein HEXIM2 is a protein that in humans is encoded by the HEXIM2 gene.[1][2]
References
- ↑ Michels AA, Nguyen VT, Fraldi A, Labas V, Edwards M, Bonnet F, Lania L, Bensaude O (Jun 2003). "MAQ1 and 7SK RNA interact with CDK9/cyclin T complexes in a transcription-dependent manner". Mol Cell Biol 23 (14): 4859–69. doi:10.1128/MCB.23.14.4859-4869.2003. PMC 162212. PMID 12832472.
- ↑ "Entrez Gene: HEXIM2 hexamthylene bis-acetamide inducible 2".
Further reading
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
- Petroziello J, Yamane A, Westendorf L, et al. (2004). "Suppression subtractive hybridization and expression profiling identifies a unique set of genes overexpressed in non-small-cell lung cancer.". Oncogene 23 (46): 7734–45. doi:10.1038/sj.onc.1207921. PMID 15334068.
- Yik JH, Chen R, Pezda AC, Zhou Q (2005). "Compensatory contributions of HEXIM1 and HEXIM2 in maintaining the balance of active and inactive positive transcription elongation factor b complexes for control of transcription.". J. Biol. Chem. 280 (16): 16368–76. doi:10.1074/jbc.M500912200. PMID 15713661.
- Byers SA, Price JP, Cooper JJ, et al. (2005). "HEXIM2, a HEXIM1-related protein, regulates positive transcription elongation factor b through association with 7SK.". J. Biol. Chem. 280 (16): 16360–7. doi:10.1074/jbc.M500424200. PMID 15713662.
- Li Q, Price JP, Byers SA, et al. (2005). "Analysis of the large inactive P-TEFb complex indicates that it contains one 7SK molecule, a dimer of HEXIM1 or HEXIM2, and two P-TEFb molecules containing Cdk9 phosphorylated at threonine 186.". J. Biol. Chem. 280 (31): 28819–26. doi:10.1074/jbc.M502712200. PMID 15965233.
- Fraldi A, Varrone F, Napolitano G, et al. (2006). "Inhibition of Tat activity by the HEXIM1 protein.". Retrovirology 2 (1): 42. doi:10.1186/1742-4690-2-42. PMC 1183248. PMID 15992410.
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