HERV-FRD
From Wikipedia, the free encyclopedia
| Endogenous retrovirus group FRD, member 1 | |||||||||||||
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 PDB rendering based on 1y4m. | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | ERVFRD-1; ERVFRDE1; GLLL6191; HERV-FRD; HERV-W/FRD; UNQ6191; envFRD | ||||||||||||
| External IDs | OMIM: 610524 MGI: 3045308 HomoloGene: 86779 GeneCards: ERVFRD-1 Gene | ||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 405754 | 239167 | |||||||||||
| Ensembl | ENSG00000244476 | ENSMUSG00000047977 | |||||||||||
| UniProt | P60508 | Q8BI41 | |||||||||||
| RefSeq (mRNA) | NM_207582 | NM_173420 | |||||||||||
| RefSeq (protein) | NP_997465 | NP_775596 | |||||||||||
| Location (UCSC) | Chr 6: 11.1 – 11.11 Mb | Chr 14: 69.29 – 69.29 Mb | |||||||||||
| PubMed search | |||||||||||||
HERV-FRD provirus ancestral Env polyprotein, also known as HERV-FRD, is a human gene.[1]
References
Further reading
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- de Parseval N, Lazar V, Casella JF, et al. (2003). "Survey of human genes of retroviral origin: identification and transcriptome of the genes with coding capacity for complete envelope proteins.". J. Virol. 77 (19): 10414–22. doi:10.1128/JVI.77.19.10414-10422.2003. PMC 228468. PMID 12970426.
- Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
- Blaise S, de Parseval N, Bénit L, Heidmann T (2004). "Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.". Proc. Natl. Acad. Sci. U.S.A. 100 (22): 13013–8. doi:10.1073/pnas.2132646100. PMC 240736. PMID 14557543.
- Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6.". Nature 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404.
- Blaise S, Ruggieri A, Dewannieux M, et al. (2004). "Identification of an envelope protein from the FRD family of human endogenous retroviruses (HERV-FRD) conferring infectivity and functional conservation among simians.". J. Virol. 78 (2): 1050–4. doi:10.1128/JVI.78.2.1050-1054.2004. PMC 368808. PMID 14694139.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Renard M, Varela PF, Letzelter C, et al. (2005). "Crystal structure of a pivotal domain of human syncytin-2, a 40 million years old endogenous retrovirus fusogenic envelope gene captured by primates.". J. Mol. Biol. 352 (5): 1029–34. doi:10.1016/j.jmb.2005.07.058. PMID 16140326.
- Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
- Malassiné A, Blaise S, Handschuh K, et al. (2007). "Expression of the fusogenic HERV-FRD Env glycoprotein (syncytin 2) in human placenta is restricted to villous cytotrophoblastic cells.". Placenta 28 (2-3): 185–91. doi:10.1016/j.placenta.2006.03.001. PMID 16714059.
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