Gregory Petsko
| Gregory Petsko | |
|---|---|
| Institutions |
Brandeis University Wayne State University MIT Max Planck Institute University of Oxford Princeton University |
| Alma mater | Princeton University |
| Thesis | Structural studies of triose phosphate isomerase. (1974) |
| Doctoral advisor | David Chilton Phillips |
| Notable awards |
Rhodes Scholarship Member of the U.S. National Academy of Sciences |
| Website | |
| www.bio.brandeis.edu/faculty/petsko.html | |
Education
Petsko was an undergraduate at Princeton University. He received a Rhodes Scholarship, and obtained his doctorate from the University of Oxford supervised David Chilton Phillips studying Triosephosphate isomerase.
Career
Petsko's independent academic career included stints at Wayne State University, the Massachusetts Institute of Technology, the Max Planck Institute, and, since 1991, Brandeis University, where he is Professor of Biochemistry and of Chemistry and Director of the Rosenstiel Center. He is Past-President of the American Society for Biochemistry and Molecular Biology. In April 2010, he was elected to the American Philosophical Society.[1]
Research
Petsko's research interests[2] are in protein crystallography. He is co-author with Dagmar Ringe of Protein Structure and Function.[3] He is also the author of a monthly column in Genome Biology[4][5] modelled after an amusing column in Current Biology penned by Sydney Brenner.[6] Petsko is best known for using X-ray crystallography to solve important problems in protein function including protein dynamics as a function of temperature and problems in mechanistic enzymology.[7][8][9]
At MIT and Brandeis, he trained a large number of current leaders in structural molecular biology who now have leadership roles in science. These individuals include:
- Tom Alber and John Kuriyan, professors at University of California, Berkeley
- Barry Stoddard and Roland Strong, faculty at Fred Hutchinson Cancer Research Center
- Ilme Schlichting, department head at Max Planck Institute for Medical Research
- Ann Stock, professor at the Howard Hughes Medical Institute and Rutgers
- Steven Almo, professor at Albert Einstein College of Medicine
- Axel Brunger, professor at Stanford University
- Charles Brenner, department head at University of Iowa
- Karen Allen, professor at Boston University
- Lynne Howell, professor at University of Toronto
- David Rose, professor at University of Waterloo
- and Stephen Burley of SGX Pharmaceuticals
References
- ↑ http://www.brandeis.edu/now/images/petskoaps.html
- ↑ List of publications from Microsoft Academic Search
- ↑ Petsko, Gregory A. (2008). Protein Structure and Function (Primers in Biology). Oxford [Oxfordshire]: Oxford University Press. ISBN 0-19-955684-9.
- ↑ Petsko, G. A. (2000). "The grail problem". Genome Biology 1 (1): comment002.comment001–comment002.comment001. doi:10.1186/gb-2000-1-1-comment002. PMC 138819. PMID 11104515.
- ↑ Petsko, G. A. (2012). "A case of the flu". Genome Biology 13 (2): 146. doi:10.1186/gb-2012-13-2-146. PMC 3334562. PMID 22364112.
- ↑ Brenner, S. (2002). "The worm's turn". Current biology : CB 12 (21): R713. PMID 12419193.
- ↑ Frauenfelder, H.; Petsko, G. A.; Tsernoglou, D. (1979). "Temperature-dependent X-ray diffraction as a probe of protein structural dynamics". Nature 280 (5723): 558–563. doi:10.1038/280558a0. PMID 460437.
- ↑ Schlichting, I.; Berendzen, J.; Chu, K.; Stock, A. M.; Maves, S. A.; Benson, D. E.; Sweet, R. M.; Ringe, D.; Petsko, G. A.; Sligar, S. G. (2000). "The Catalytic Pathway of Cytochrome P450cam at Atomic Resolution". Science 287 (5458): 1615–1622. doi:10.1126/science.287.5458.1615. PMID 10698731.
- ↑ Karplus, M.; Petsko, G. A. (1990). "Molecular dynamics simulations in biology". Nature 347 (6294): 631–639. doi:10.1038/347631a0. PMID 2215695.
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