Goblet cell carcinoid
From Wikipedia, the free encyclopedia
| Goblet cell carcinoid | |
|---|---|
| Classification and external resources | |
 Micrograph showing a goblet cell carcinoid. H&E stain. |
The goblet cell carcinoid, abbreviated GCC and also known as crypt cell carcinoma and neuroendocrine tumour with goblet cell differentiation, is a rare biphasic gastrointestinal tract tumour that consists of a neuroendocrine component and a conventional carcinoma, histologically arising from Paneth cells.[1]
Sign and symptoms
GCCs may present as appendicitis.
Diagnosis
Micrograph of a goblet cell carcinoid. H&E stain.
GCCs are diagnosed by pathology. They have a characteristic biphasic appearance which includes (1) goblet cell-like cells, and (2) neuroendocrine-type nuclear chromatin (stippled chromatin).
Prognosis
GCCs have an aggressive course vis-a-vis other appendiceal neuroendocrine tumours.[1]
Treatment
GCCs are treated with surgery.
See also
- Neuroendocrine tumours
References
- ↑ 1.0 1.1 van Eeden S, Offerhaus GJ, Hart AA, et al. (December 2007). "Goblet cell carcinoid of the appendix: a specific type of carcinoma". Histopathology 51 (6): 763–73. doi:10.1111/j.1365-2559.2007.02883.x. PMID 18042066.
This article is issued from Wikipedia. The text is available under the Creative Commons Attribution/Share Alike; additional terms may apply for the media files.