Gestonorone

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Gestonorone

Systematic (IUPAC) name
(8R,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-13-methyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
Clinical data
Legal status	?
Identifiers
CAS number	2137-18-0
ATC code	G03DA01 L02AB03
PubChem	CID 102210
ChemSpider	92341^Y
UNII	H4G605B7VP^Y
Chemical data
Formula	C₂₀H₂₈O₃
Mol. mass	316.435 g/mol
SMILES O=C4\C=C2/[C@@H]([C@H]1CC[C@@]3([C@@](O)(C(=O)C)CC[C@H]3[C@@H]1CC2)C)CC4
InChI InChI=1S/C20H28O3/c1-12(21)20(23)10-8-18-17-5-3-13-11-14(22)4-6-15(13)16(17)7-9-19(18,20)2/h11,15-18,23H,3-10H2,1-2H3/t15-,16+,17+,18-,19-,20-/m0/s1^Y Key:GTFUITFQDGVJSK-XGXHKTLJSA-N^Y
Y (what is this?) (verify)

Gestonorone (or 17-nydroxy-19-norprogesterone) is a steroidal progestin.

References

Agonist

1st	Norpregnene Norethisterone^#/Norethisterone acetate Etynodiol diacetate

2nd	Norpregnene Levonorgestrel^#/Norgestrel/Norelgestromin

3rd	19-Nortestosterone Desogestrel/Etonogestrel Gestodene Norgestimate

4th	Androstene Drospirenone 19-Norprogesterone Nomegestrol acetate Promegestone Trimegestone 19-Nortestosterone Dienogest

17-OH	Chlormadinone acetate Cyproterone acetate Medroxyprogesterone acetate^# Megestrol acetate

Other/ ungrouped	Pregnenedione Gestonorone Pregnene Ethisterone Pregnadiene Medrogestone Norpregnane Norgestrienone Lynestrenol Norethynodrel Tibolone Dydrogesterone Quingestanol

Agonists

Steroidal	Diosgenin Estetrol Estradiol Estradiol acetate Estradiol benzoate Estradiol cypionate^# Estradiol dipropionate Estradiol enanthate Estradiol hemihydrate Estradiol undecylate Estradiol valerate Polyestradiol phosphate Estriol Estriol succinate Estrone Estrone sulfate Estriol Ethinylestradiol^# Mestranol Promestriene Equilenin Equilin

Nonsteroidal	Chlorotrianisene Dienestrol Fosfestrol Diethylstilbestrol Zeranol

Selective: Anastrozole; Atamestane; Exemestane; Fadrozole; Formestane; Letrozole; Minamestane; Plomestane; Vorozole

M: ♀ FRS

anat/phys/devp

noco/cong/npls, sysi/epon

proc/asst, drug (G1/G2B/G3CD)

PR (A, B)

20,22-Desmolase	22-ABC 3,3′-Dimethoxybenzidine 3-Methoxybenzidine Aminoglutethimide Cyanoketone Danazol Etomidate Mitotane Trilostane

17α-Hydroxylase, 17,20-Lyase	22-ABC 22-Oxime Abiraterone Bifonazole Clotrimazole Cyanoketone Cyproterone acetate Danazol Econazole Galeterone Gestrinone Isoconazole Ketoconazole L-39 Levonorgestrel Liarozole LY-207,320 MDL-27,302 Miconazole Mifepristone Orteronel Pioglitazone Rosiglitazone Spironolactone Stanozolol SU-10,603 TGF-β Tioconazole Troglitazone VN/87-1 YM116

3β-HSD	4-MA Azastene Cyanoketone Danazol Epostane Genistein Gestrinone Metyrapone Norethisterone Oxymetholone Pioglitazone Rosiglitazone Trilostane Troglitazone

21-Hydroxylase	Aminoglutethimide Amphenone B Bifonazole Clotrimazole Diazepam Econazole Genistein Isoconazole Ketoconazole Metyrapone Miconazole Midazolam Tioconazole

Other

Endogenous	Progestogens: Deoxycorticosterone 17-Hydroxyprogesterone Progesterone Precursors: Cholesterol 22R-Hydroxycholesterol 20α,22R-Dihydroxycholesterol Pregnenolone 17-Hydroxypregnenolone

Indirect	Androgens/Antiandrogens (see here) Estrogens/Antiestrogens (see here) GnRH agonists/antagonists (see here) Gonadotropins/Antigonadotropins (see here) Plasma proteins (Transcortin, Albumin)

Procedures	Adrenalectomy Hypophysectomy Oophorectomy Orchiectomy

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