GPR61
From Wikipedia, the free encyclopedia
| G protein-coupled receptor 61 | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||
| Symbols | GPR61; BALGR; GPCR3 | ||||||||||||
| External IDs | OMIM: 606916 MGI: 2441719 HomoloGene: 12910 IUPHAR: GPR61 GeneCards: GPR61 Gene | ||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 83873 | 229714 | |||||||||||
| Ensembl | ENSG00000156097 | ENSMUSG00000046793 | |||||||||||
| UniProt | Q9BZJ8 | Q8C010 | |||||||||||
| RefSeq (mRNA) | NM_031936 | NM_175470 | |||||||||||
| RefSeq (protein) | NP_114142 | NP_780679 | |||||||||||
| Location (UCSC) | Chr 1: 110.08 – 110.09 Mb | Chr 3: 108.15 – 108.15 Mb | |||||||||||
| PubMed search | |||||||||||||
Probable G-protein coupled receptor 61 is a protein that in humans is encoded by the GPR61 gene.[1][2][3]
This gene belongs to the G-protein coupled receptor 1 family. G protein-coupled receptors contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. The protein encoded by this gene is most closely related to biogenic amine receptors.[3]
References
- ↑ Lee DK, George SR, Cheng R, Nguyen T, Liu Y, Brown M, Lynch KR, O'Dowd BF (Feb 2001). "Identification of four novel human G protein-coupled receptors expressed in the brain". Brain Res Mol Brain Res 86 (1–2): 13–22. doi:10.1016/S0169-328X(00)00242-4. PMID 11165367.
- ↑ Cikos S, Gregor P, Koppel J (Nov 2001). "Cloning of a novel biogenic amine receptor-like G protein-coupled receptor expressed in human brain". Biochim Biophys Acta 1521 (1–3): 66–72. PMID 11690637.
- ↑ 3.0 3.1 "Entrez Gene: GPR61 G protein-coupled receptor 61".
Further reading
- Gregory SG, Barlow KF, McLay KE et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.
- Kimura K, Wakamatsu A, Suzuki Y et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
- Conner AC, Hay DL, Simms J et al. (2005). "A key role for transmembrane prolines in calcitonin receptor-like receptor agonist binding and signalling: implications for family B G-protein-coupled receptors". Mol. Pharmacol. 67 (1): 20–31. doi:10.1124/mol.67.1. PMID 15615699.
- Gerhard DS, Wagner L, Feingold EA et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Strausberg RL, Feingold EA, Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Takeda S, Kadowaki S, Haga T et al. (2002). "Identification of G protein-coupled receptor genes from the human genome sequence". FEBS Lett. 520 (1–3): 97–101. doi:10.1016/S0014-5793(02)02775-8. PMID 12044878.
See also
- GPR61 receptor, human at the US National Library of Medicine Medical Subject Headings (MeSH)
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