Flurithromycin

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Flurithromycin

Systematic (IUPAC) name
(3R,4S,5S,6R,7R,9S,11R,12R,13S,14R)-6- [(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy- 6-methyloxan-2-yl]oxy-14-ethyl-9-fluoro-7,12, 13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy- 4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9, 11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione
Clinical data
Legal status	?
Identifiers
CAS number	82664-20-8
ATC code	J01FA14
PubChem	CID 71260
ChemSpider	64388^Y
UNII	56C9DTE69V^Y
KEGG	D07242^Y
Chemical data
Formula	C₃₇H₆₆F N O₁₃
Mol. mass	751.917 g/mol
SMILES O=C3O[C@H](CC)[C@](O)(C)[C@H](O)[C@H](C(=O)[C@](F)(C)C[C@](O)(C)[C@H](O[C@@H]1O[C@H](C)C[C@H](N(C)C)[C@H]1O)[C@H]([C@H](O[C@@H]2O[C@H]([C@H](O)[C@](OC)(C2)C)C)[C@H]3C)C)C
InChI InChI=1S/C37H66FNO13/c1-14-24-37(10,46)29(42)21(5)28(41)34(7,38)17-35(8,45)31(52-33-26(40)23(39(11)12)15-18(2)48-33)19(3)27(20(4)32(44)50-24)51-25-16-36(9,47-13)30(43)22(6)49-25/h18-27,29-31,33,40,42-43,45-46H,14-17H2,1-13H3/t18-,19+,20-,21+,22+,23+,24-,25+,26-,27+,29-,30+,31-,33+,34+,35-,36-,37-/m1/s1^Y Key:XOEUHCONYHZURQ-HNUBZJOYSA-N^Y
Y (what is this?) (verify)

Flurithromycin is a macrolide antibiotic. It is a fluorinated derivative of erythromycin.

Antibacterials: protein synthesis inhibitors (J01A, J01B, J01F, J01G, QJ01XQ)

Aminoglycosides
(initiation inhibitors)

-mycin (Streptomyces)	Streptomycin^# Dihydrostreptomycin Neomycin^# Framycetin Paromomycin Ribostamycin Kanamycin^# Amikacin Arbekacin Bekanamycin Dibekacin Tobramycin Spectinomycin^# Hygromycin B Paromomycin

-micin (Micromonospora)	Gentamicin^# Netilmicin Sisomicin Isepamicin Verdamicin Astromicin

Tetracyclines	Doxycycline^# Chlortetracycline Clomocycline Demeclocycline Lymecycline Meclocycline Metacycline Minocycline Oxytetracycline Penimepicycline Rolitetracycline Tetracycline

Glycylcyclines	Tigecycline

Oxazolidinone
(initiation inhibitors)

Amphenicols	Chloramphenicol^# Azidamfenicol Thiamphenicol Florfenicol

Pleuromutilins	Retapamulin Tiamulin Valnemulin

MLS (transpeptidation/translocation)

Macrolides	Azithromycin^# Clarithromycin Dirithromycin Erythromycin^# Flurithromycin Josamycin Midecamycin Miocamycin Oleandomycin Rokitamycin Roxithromycin Spiramycin Troleandomycin Tylosin Ketolides Telithromycin Cethromycin Solithromycin^†

Lincosamides	Clindamycin^# Lincomycin Pirlimycin

Streptogramins	Pristinamycin Quinupristin/dalfopristin Virginiamycin

Steroid antibacterials	Fusidic acid

bact (clas)

gr+f/gr+a (t)/gr-p (c)/gr-o

drug (J1p, w, n, m, vacc)

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