Fluperolone acetate

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Fluperolone acetate
Systematic (IUPAC) name
(2S)-1-[(1R,2S,10S,11S,14R,15S,17S)-1-fluoro-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-dien-14-yl]-1-oxopropan-2-yl acetate
Clinical data
Legal status ?
Identifiers
CAS number 2119-75-7
ATC code D07AB05
PubChem CID 66257
Synonyms [(2S)-1-[(8S,9S,10S,11S,13S,14S,17R)-9-fluoro-11,17-dihydroxy-10,13-dimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-1-oxo-propan-2-yl] acetate
Chemical data
Formula C24H31FO6 
Mol. mass 434.498 g/mol
 YesY (what is this?)  (verify)

Fluperolone acetate is a corticosteroid.

Fluperolone has been used topically.[1]

References

  1. ↑ THORNE N (March 1963). "A clinical trial of Fluperolone, a new topical steroid". Postgrad Med J 39: 159–60. doi:10.1136/pgmj.39.449.159. PMC 2482046. PMID 13984971. 


Corticosteroids – glucocorticoids and mineralocorticoids (H02)
(also A07EA, C05AA, D07, D10AA, R01AD, R03BA, S01BA, S02B, and S03B)
Mineralocorticoids
(3-one, 4-ene,
no FG at 16)
Glucocorticoids
(3-one, 4-ene,
11-FG,
17-hydroxy)
Pregnenedione
(+20-one)
Pregnadiene (+1-ene)
Pregnadienediol
(+21-hydroxy)
Pregnadienetriol
(+11-hydroxy)
Pregnatriene
(+2-ene)
Other/ungrouped
Aldosterone antagonists
Synthesis modifiers

M: END

anat/phys/devp/horm

noco (d)/cong/tumr, sysi/epon

proc, drug (A10/H1/H2/H3/H5)


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