Fluorometholone

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Fluorometholone
Systematic (IUPAC) name
(1R,2S,8S,10S,11S,14R,15S,17S)-14-acetyl-1-fluoro-14,17-dihydroxy-2,8,15-trimethyltetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-dien-5-one
Clinical data
AHFS/Drugs.com monograph
MedlinePlus a682660
Pregnancy cat. C
Legal status ?
Identifiers
CAS number 426-13-1 YesY
ATC code C05AA06 D07AB06, D07XB04 (combinations), D10AA01, S01BA07
PubChem CID 9878
DrugBank DB00324
ChemSpider 9494 YesY
UNII SV0CSG527L YesY
KEGG D01367 YesY
ChEMBL CHEMBL1200600 N
Synonyms (6S,8S,9R,10S,11S,13S,14S,17R)-17-acetyl-9-fluoro-11,17-dihydroxy-6,10,13-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
Chemical data
Formula C22H29FO4 
Mol. mass 376.462 g/mol
 N (what is this?)  (verify)

Fluorometholone is a corticosteroid, most often used after laser-based refractive surgery. It is marketed under the brand names FML (Allergan) and Flarex (Alcon).

Fluorometholone acetate ophthalmic suspension is indicated for use in the treatment of steroid responsive inflammatory conditions of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the eye.

See also

References

    External links


    Antihemorrhoidals for topical use
    corticosteroids
    local anesthetics
    other
    Antivaricose therapy
    heparins or heparinoids for topical use
    sclerosing agents for local injection
    other
    Capillary stabilising agents
    bioflavonoids
    other

    M: VAS

    anat (a:h/u/t/a/l,v:h/u/t/a/l)/phys/devp/cell/prot

    noco/syva/cong/lyvd/tumr, sysi/epon, injr

    proc, drug (C2s+n/3/4/5/7/8/9)

    Corticosteroids – glucocorticoids and mineralocorticoids (H02)
    (also A07EA, C05AA, D07, D10AA, R01AD, R03BA, S01BA, S02B, and S03B)
    Mineralocorticoids
    (3-one, 4-ene,
    no FG at 16)
    Glucocorticoids
    (3-one, 4-ene,
    11-FG,
    17-hydroxy)
    Pregnenedione
    (+20-one)
    Pregnadiene (+1-ene)
    Pregnadienediol
    (+21-hydroxy)
    Pregnadienetriol
    (+11-hydroxy)
    Pregnatriene
    (+2-ene)
    Other/ungrouped
    Aldosterone antagonists
    Synthesis modifiers

    M: END

    anat/phys/devp/horm

    noco (d)/cong/tumr, sysi/epon

    proc, drug (A10/H1/H2/H3/H5)


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